25Mar 2017

EVALUATION OF GLOBAL LV FUNCTION AND MECHANICAL DYSSYNCHRONY IN PATIENTS WITH LEFT BUNDLE BRANCH BLOCK (LBBB) - 2D ECHOCARDIOGRAPHY, 2D SPECKLE TRACKING AND REAL TIME 3D ECHOCARDIOGRAPHY.

  • Professor and HOD, Department of Cardiology, J. N. Medical College, Belgaum , Karnataka, India-590001.
  • Associate Professor, Department of Cardiology, J. N. Medical College, Belgaum , Karnataka,India-590001.
  • Professor, Department of Cardiology, J. N. Medical College, Belgaum , Karnataka, India-590001.
  • Senior Resident, Department of Cardiology J. N. Medical College, Belgaum, Karnataka, India-590001.
  • Msc Post Graduate, Department of Cardiology J. N. Medical College, Belgaum, Karnataka, India-590001.
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Background: LBBB affects LV function and causes LV mechanical dyssynchrony. Prevalence of LBBB increases with age about 0.05% to 5.7% between age of 30-80 years in otherwise healthy population. Aim of the study was to evaluate the LV function and mechanical dyssynchrony with 2D Echocardiography, 2D speckle tracking and real time 3D Echocardiography (RT3DE) in asymptomatic LBBB patients, non- LBBB volunteers, and with symptomatic LBBB patients. Methods: 2D Echocardiography, 2D speckle tracking and real time 3D Echocardiography was performed in 191 patients, 65 were non- LBBB volunteers, 60 patients were asymptomatic LBBB and 66 patients were symptomatic LBBB patients. Global LV function and mechanical dyssynchrony were measured. Results: Non LBBB volunteers mean LV ejection fraction by 2D Echo was 67.18± SD 3.45, in RT3DE mean LV ejection fraction was 61.88±SD 3.12. In asymptomatic LBBB patients LVEF by 2D was 58.43± and RT3DE LVEF was 54.47± 4.08. In heart failure (HF) with LBBB patients 2D LVEF was 43.53±7.12 and 3D LVEF 39.21±7.97. LV dyssynchrony measurements by 2D speckle tracking analysis showed: A. Sdt of 6S segments by CS was54.82±11.2, 96.43±17.73, 119.02±23.17 for non-LBBB volunteers, asymptomatic LBBB patients and symptomatic LBBB patients respectively. B. Sdt of 12S by LS was 52.96±5.1, 90.03±16.2, 111.75±34.22 for non-LBBB volunteers, asymptomatic LBBB patients and symptomatic LBBB patients respectively. Systolic dyssynchrony (SDI) index by RT3DE was 5.07±2.22, 7.44± 1.45, 15.08±3.85 for non-LBBB volunteers, asymptomatic LBBB patients and symptomatic LBBB patients respectively. Conclusion:Asymptomatic LBBB patients have more depressed LV function than non LBBB volunteers with intermediate mechanical dyssynchrony, symptomatic LBBB patients have moderate to severe LV dysfunction and most severe mechanical dyssynchrony among the 3 groups.

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[Dr Suresh V Patted, Dr Sanjay C Porwal, Dr Prabhu C Halkati, Dr Sameer Ambar, Dr Prasad M R, Dr V.B Metgudmath, Dr Vishwanath Hesarur, Dr Anand Kumar M and Dr Shakuntala (2017); EVALUATION OF GLOBAL LV FUNCTION AND MECHANICAL DYSSYNCHRONY IN PATIENTS WITH LEFT BUNDLE BRANCH BLOCK (LBBB) - 2D ECHOCARDIOGRAPHY, 2D SPECKLE TRACKING AND REAL TIME 3D ECHOCARDIOGRAPHY. Int. J. of Adv. Res. 5 (Mar). 729-740] (ISSN 2320-5407). www.journalijar.com

Dr Anand Kumar
JN Medical College,KLE University,Belagavi

DOI:

Article DOI: 10.21474/IJAR01/3565      
DOI URL: https://dx.doi.org/10.21474/IJAR01/3565

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