A COMPARATIVE CLINICAL AND RADIOLOGICAL STUDY USING BIOGRAFT-HABG ACTIVE AND BIOGRAFT ?CPC.

Background and objectives: This clinical study was carried out on 20 systemically healthy subjects to evaluate and compare, clinically and radiographically, the efficacy of Bioactive composite granule (Biograft-HABG Active) and Calcium phosphate cement (Biograft-CPC) in the treatment of periodontal endosseous defects clinically and radiographically and compare them. Methodology: 20 intrabony defects present in 20 patients, who fulfilled the inclusion and exclusion criteria were selected and divided into two groups. Group I received bioactive composite granule, Group II received calcium phosphate cement. Clinical and radiological parameters such as Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD), Clinical Attachment Level (CAL), Gingival recession (GR) and Depth of the bone defect (BL) were assessed at baseline 3, 6 and 9 months post operatively. The results were averaged for each clinical and radiological parameter at baseline, 3 months, 6 months and 9 months. Results: Statistically significant difference in mean values of the plaque index, gingival index, pocket depth reduction, clinical attachment level, gain amount of defect resolution were observed in both the groups at subsequent time periods. Conclusion: Clinical and radiographic assessments reveal that both bone graft materials were efficacious in the treatment of periodontal endosseous defects and have nearly comparable effects. However, long-term, multicenter randomized, controlled clinical trials will be required to discern the definite clinical and radiographic effects of these graft materials and to arrive at an explicit conclusion.