CHARACTERIZATION AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF CLINICAL ISOLATES OF ENTEROCOCCI AT A TERTIARY CARE HOSPITAL IN BHAVNAGAR, GUJARAT.
- Abstract
- Keywords
- References
- Cite This Article as
- Corresponding Author
Enterococcal infection is a life threatening systemic infection prevalent in developing countries like India and is a major public health problem.Enterococciare important nosocomial pathogen of human disease; second most common cause of nosocomial urinary tract and wound infections; third most common cause of nosocomial bacteremias. Because of their resistance to different antimicrobial agents these bacteria are often involved in serious super-infections among patients receiving broad-spectrum anti-microbial therapy. Correct diagnosis is crucial in proper management of Enterococcal infection, so laboratory tests are essential to establish identification of Enterococcal species. The study was conducted to isolate and characterize Enterococcus species from different clinical samples and to perform antimicrobial susceptibility testing in all age groups and both genders. Out of 200 Enterococcal species isolated, 164 (82%) were E. faecalis and 34 (17%) were E. faecium; majority were isolated from urine (60%) and blood (35.5%); they showed more resistance to penicillin (92%), less resistance to vancomycin (1%) and no resistance to linezolid (0%).
- Koneman EW, Allen SD, Janda WM, Schreckenberger PC, Winn WC. Color Atlas and Textbook of Diagnostic Microbiology. 6th Philadelphia: Lippincott; 2006; 700-705.
- Forbes BA, Sahm DF, Weissfeld AS. Tille PM. Bailey and Scott?s Diagnostic microbiology. 13th Mosby: Elsevier; 2014.
- Ananthanarayan R, Paniker CKJ. Textbook of Microbiology. Hyderabad; Orient Blackswan Private Limited; 2013; 9th ed : 217-218.
- Susan L Fraser, MD, Robert A Salata, MD, Curtic J Donskey, MD. Enterococcal Infections. Medscape Updated, June 2015.
- Mulla et al. Prevalence of Enterococci with higher resistance level in a tertiary care hospital: A matter of concern. National Journal of Medical Research. 2012, vol 2, issue 1, p: 25-27.
- Performance standards for antimicrobial susceptibility testing. CLSI twenty first informational supplement M100-S21. 2011; 31(1).
- Rajkumari et al. Magnitude of Enterococcal bacteria in trauma patients admitted from intensive trauma care; A tertiary care experience from South Asian country. J of Lab Physician. 2015, vol 7, issue 1, p: 38-42.
- Sarita et al. Antibiotic resistance in fecal Enterococcal in hospitalized patients. IJPM. 2010, 53(4), 898-899.
- Monika Cheesbrough. District Laboratory Practice in Tropical Countries. 2nd edition, update, part-2. Cambridge, New Delhi, 2012, p-69,165.
- PJ Desai, D Pandit, M Mathur, A Gogate. Prevalence, identification and distribution of various species of enterococci isolated from clinical specimens with special reference to urinary tract infection in catheterized patients. IJMM, Year: 2001, Volume : 19, Issue : 3, Page : 132-137
- Aher CS et al. Vancomycin resistant Enterococci, An emerging threat. Int. J. Curr. Microbiol. App. Scie. 2014, vol 3 (2), 14-19.
- Jawetz, Melnick, Adelberg. Medical Microbiology; 24th ed, Mc Graw Hill, 2007, 254-259.
- Vidyalakshmi PR,Gopala Krishnan R, RamasubramanianV et al. Clinical, Epidemiological, and Microbiological Profile of Patients with Vancomycin-Resistant Enterococci from a Tertiary Care Hospital. J Glob Infect Dis. 2012 Apr-Jun; 4(2): 137?138.
- Bose S, Ghosh AK, Barapatre R et al. Prevalence of drug resistance among Enterococcus spp isolated from a Tertiary Care Hospital. International Journal of Medical and Health Sciences, ISSN 2277-4505.
- Gupta et al. Antimicrobial susceptibility pattern of vancomycin resistant Enterococci to newer antimicrobial agents. Indian J. Med. Res. 141, 2015, 483-486.
- Grey JW, David S, Pedler SJ. Species identification and antimicrobial susceptibility testing of Enterococci isolated from hospitalized patients. 1991, vol 35, no 9, 1943-1945.
- Agrawal J, Rajkumar K, Singh M. High level Aminoglycoside resistance and β-lactamase production in Enterococci at a tertiary care hospital in India. Jpn. J. Infec. Dis, 2009, 62, 158-159.
- Bhatt MP, Patel A, Sahni AK, et al. Emergence of multidrug resistant enterococci at a tertiary care center. Med Journal ARMED India, 71 (2015) 139-144.
- HP Nepal, B Khanal, A Acharya et al. Characterization and antimicrobial resistance of clinical isolates of enterococci in tertiary care hospital in eastern Nepal. Health Renaissance 2013; Vol. 11 No. 1; 17-22.
- Saraswathy P, Karunakaran S, Narayanan S. Antimicrobial resistance profile and characterization of Enterococcus species from various clinical sample in a tertiary care hospital. Int. J. of Med. Res. Health Scie. 2013, vol 2 (3), 328-333.
[Dhvani D. Parmar. (2017); CHARACTERIZATION AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF CLINICAL ISOLATES OF ENTEROCOCCI AT A TERTIARY CARE HOSPITAL IN BHAVNAGAR, GUJARAT. Int. J. of Adv. Res. 5 (Mar). 777-781] (ISSN 2320-5407). www.journalijar.com
Microbiology Department, Govt Medical College & Sir T Hospital, Bhavnagar, Gujarat.