PENETRATING KERATOPLASTY: INDICATION, OUTCOMES, AND COMPLICATION.

Purpose:This study is a modest and a humble attempt done with purpose of: analyzing the overall survival rate of corneal transplants, studying the various factors influencing the survival of the graft and studying the post-operative complications and correlating it with the several pre-operative, intra-operative and post-operative factors. Methods: This prospective case note review identified 50 penetrating keratoplasties [25: Optical & 25: Therapeutic] performed during a period from Sept.2015 to Aug.2016 at S. S. G. Hospital, Vadodara (India). All the patients were followed for a minimum period of 3 months. Throughout the statistical analysis, the patients were divided into two major groups: Optical and Therapeutic. Preoperative risk factor, surgical technique, postoperative complications were analyzed. Results: Maximum incidence of KP [52%] was seen in the age group >60 years [males and females inclusive].Most frequent indication for OKP in the study cases was corneal leucomatous opacities [44%], followed by Pseudophakic Bullous Keratopathy [32%]. The age of majority of donor eyeballs was more than 60 years [68%] or between 41-60 years [26%] {Total: 94%}. The most common post-operative complications noticed were Vascularization [44%] Immune rejection [34%] glaucoma [26% ]Uveitis [14%] and infection [20%]. The most probable causes of failure in Optical and Therapeutic cases were: Complications after surgery, Immune rejection reaction and Primary Endothelial failure.