ANTIMICROBIAL ACTIVITY OF ALKALOID EXTRACT FROM THE LEAVES OF ZYGOPHYLLUM FABAGO.

  • Department of Pathology, College of Medicine, Al-Nahrain University.
Crossref Cited-by Linking logo

  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Due to the risk properties of commercial biocides, plant-based biocides may proposal a safer alternative for control microbes that cause sick building syndrome and building deterioration. The aim of the study was to determine a new source of bioactive extracts from plants. Alkaloid extract from leaves of Zygophyllum fabago, was screened for potential antimicrobial activity against one species of bacteria (Bacillus subtilis) and four filamentous fungi (Aspergillus flavus, Aspergillus niger, Penicillium oxalicum and Cladosporium oxysporum) isolated from enclosed sick buildings. The minimum inhibitory concentration against the highly sensitive microorganisms i.e. B. subtilis and P. oxalicum was 0.157 and 0.635 mg/ml, respectively.

  1. Abdel-Hamid R. A. (2014). Investigation of chemical constituents and biological activities of some native halophytes, Doctor of Philosophy (PhD), Al-Farabi Kazakh National University, Republic of Kazakhstan, Almaty: 147 pp.
  2. Al-Mokhtar J.A.H. (1971). Zygophyllaceae of Iraq (taxonomy and economic important). Ministry of Agriculture of the Republic of Iraq, Abu Graib: 35 pp.
  3. Banso A. and Adeyemo S. (2006). Phytochemical screening and antimicrobial assessment of Abutilon mauritianum, Bacopa monnifera and Datura stramonium. Biokemistri, 18: 39-44.
  4. Bhattacharyya B. and Johri B. M. (1998). Flowering Plants Taxonomy and Phylogeny, S. Springer Verlag, Berlin, Heidelberg, New York: 753 pp.
  5. Burge P. (2004). Sick building syndrome. Occup. Environ. Med., 61: 185-190.
  6. Chester A. and Levine, P. (1997).The natural history of concurrent Sick Building Syndrome and Chronic Fatigue Syndrome. Psych. Res., 31(1): 51-57.
  7. Cooley J., Wong W., Jumper C. and Straus D. (1998). Correlation between the prevalence of certain fungi and sick building syndrome. Environ. Med., 55: 579-584.
  8. Dana E. D., Delomas J. G. and Sanchez J. (2010). Effects of the aqueous extracts of Zygophyllum fabago on the growth of Fusarium oxyosporum sp. melonis and Pythium aphanidermatum. Weed Biol. Manag., 10: 170?175.
  9. Feng Y. L., Wu B., Li H. R., Li Y. Q., Xu L. Z., Yang S. L. and Kitanaka S. (2008). Triterpenoidal saponins from the barks of Zygophyllum fabago Chem. Pharm. Bull., 56: 858-860.
  10. Gnan S.O. and Sheriha G.M. (1986). Antimicrobial activity of (+) ? turbine,? J. Food Protec., 49 (5): 340-341.
  11. Green C.F. and Scarpino P.V. (2002). The use of ultraviolet germicidal irradiation (UVGI) in disinfection of airborne bacteria. Engin. and Pol., 3:101-107.
  12. Harborne J.B. (1984). Phytochemical methods. 2. New York: Chapman and Hall;
  13. Henrickson C.H., Byrd L.C. and Hunter N. W. (1997). A laboratory for general, organic and biochemistry, 2nd. WCB/ McGraw-Hill.
  14. Hyv?rinen A., Meklin, T., Veps?l?inen, A. and Neralainen, A. (2002). Fungi and actinobacteria in moisture damaged building materials-Concentrations and diversity. Biodeteriorat. and Biodegrad., 49:27-37.
  15. Jayanthy A., Prakash K. U. and Remashree A. B. (2013). Seasonal and Geographical Variations in Cellular Characters and Chemical Contents in Desmodium gangeticum (L.) DC. An Ayurveda Medicinal Plant. Int. J. Herbal Med. 1 (1): 34-37.
  16. Jose-Abod M., Ansuategui M. and Bermejo, P. (2007). Active antifungal substances from natural source. ARKivoc, vii: 116-145.
  17. Kang S.P., Kab C.K., Jai H. K., Adams D.J., Jung T.N. and Yong K.P. (1999). Differential inhibitory effects of protobeer beeriness on sterol and chitin biosynthesis in Candida albicans. J. Antimicrob. Chemother., 34: 667-674.
  18. Khan S.S., Khan, A. Khan, A. Wadood, A., Farooq U., Ahmed, A., Zahoor A., Ahmad V.U., Sener B. and Erdemoglu N., (2014). Urease inhibitory activity of ursane type sulfated saponins from the aerial parts of Zygophyllum fabago Phytomedicine, 21(3): 379-382.
  19. Mohammed N. T., Zeki L. S. and Majeed I. A. (2013). Antibacterial activity of Zygophllum fabago Leaves extracts. J. Al-Nahrain Univ., 16 (2): 163-166.
  20. Mukherjee B. K. (2002). Quality control herbal drugs and approach to evaluation of botanicals, New Delhi: Business Horizon: 256.
  21. Murray B. R., Baron E. J. and Pfaller M. A. (1995). Manual of Clinical Microbiology 6thed; Vol. 6, Washington DC: ASM Press, 156-208.
  22. Okoye E.I. (2015). The effect of alkaloids and flavonoids extracts of Vitex doniana seed on some microorganisms. Int. J. Cancer, Clin. Invent. and Exper. Oncol., 1(1):19-23.
  23. Sabahi M., Ramezanian M., Jaffari G., Heravi G. and Bahaeddini (1985). Survey of Iranian Plants for Saponins, Alkaloids, Flavonoids, and Tannins. IV. The Plants of Kerman Province,? Int. J. Crude Drug Res., 23(4): 165-175.
  24. Salleh B. and Sulaiman B. (1984). Fusaria associated with naturally diseased plants in Penang. J. Plant Prot. Trop., 1: 47-53.
  25. (2012). Sas/Salt users guide for personal computers, release 7.0 Sas. Inst. Inc. Cry. New York.
  26. Srikanth P., Sudharsanam S. and Steinberg R. (2008). Bio-aerosols in indoor environment: Composition, health effects, and analysis. J. Med. Microbiol., 26: 302-312.
  27. Torssel K. B. (1997). Natural product chemistry (Amechanistic, biosynthetic and ecological approach), 2nd. Ap otekarsocietten, kristianstads Boktryckeri: 480 pp.
  28. Verma R., Chaurasia L. and Katiyar S. (2008). Potential antifungal plants for controlling building fungi. Nat Prod. Rad., 7: 374-387.
  29. Wardah A. R., Hafizi R., Siti Nurdijati B. and Salleh B. (2011). Incidence and remediation of fungi in sick building in Malaysia-A case study. Aerobiologia. DOI: 10.1007/s 10453-09226-y.
  30. Wink M. (1997). Special nitrogen metabolism. In: Dey, P. M. and Harborne, J.B. (Eds.), Plant biochemistry Academic press LLCC, Florida: 439- 486.
  31. Zaidi M. A. and Crow Jr. S. A. (2005). Biologically active traditional medicinal herbs from Balochistan. J. Ethnopharmacol., 96: 331-334.
  32. Zaidi M. A. and Crow Jr. S. A. (2012). Cytotoxicity of four medical plants of Pakistan. Pak. J. Bot., 44: 395-397.
  33. Zaree R., Farhadi M., Mohammdzadeh Z. and Goudarzi G. R. (2013). Extraction and comparison of alkaloids in different organs during different phonological periods of Nitraria schoberi. Ann. Biologic. Res., 4 (2):130-135.
  34. Zhu H., Phelan P.E., Duan T., Raupp G.B., Fernando H.J.S. and Che F. (2003). Experimental study of indoor and outdoor airborne bacterial concentration in Tempe, A, Arizona, USA. Aerobiologia, 19: 201-211.

[Fahem M. Mahmood. (2017); ANTIMICROBIAL ACTIVITY OF ALKALOID EXTRACT FROM THE LEAVES OF ZYGOPHYLLUM FABAGO. Int. J. of Adv. Res. 5 (May). 1302-1306] (ISSN 2320-5407). www.journalijar.com

Fahem M. Mahmood
Department of Pathology, College of Medicine, Al-Nahrain University, Baghdad, Iraq

DOI:

Article DOI: 10.21474/IJAR01/4247      
DOI URL: https://dx.doi.org/10.21474/IJAR01/4247

Download Full Paper

Download PDF No. of Downloads: 26 | No. of Views: 628