MAGNETIC RESONANCE SPECTROSCOPY AND THE METABOLIC FINGERPRINT OF MALIGNANT MAXILLOFACIAL TUMORS.A DIAGNOSTIC ACCURACY STUDY.

  • Assistant lecturerofOral and Maxillofacial Radiology, Faculty of Oral and Dental Medicine, Cairo University; Cairo, Egypt.
  • Ass. Professor of Oral and Maxillofacial Radiology, Faculty of Oral and Dental Medicine, Cairo University; Cairo, Egypt.
  • Professor of Oral and Maxillofacial Radiology, Faculty of Oral and Dental Medicine, Cairo University; Cairo, Egypt.
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Objective: The purpose of this study was to define the malignant metabolic profile of maxillofacial lesions using Magnetic resonance spectroscopy. Subjects and Methods:Twenty-one patients with maxillofacial lesions were enrolled in this study through consecutive sampling.Single-voxel MRS was performed using a spin echo (point resolved spectroscopy) sequence. Qualitative and semi-quantitative analyses were performed to assess the choline and lactate peaks in benign and malignant lesions. Results: Statistical analysis showed that there was a significant difference between the mean of both metabolites in benign and malignant entities. The diagnostic accuracy of lactate was higher than that of choline. Threshold values of > 0.125 and 0.336 for lactate and choline were extracted in a trial to differentiate between both entities. Conclusion:Magnetic resonance spectroscopy is a state-of-art in the diagnostic arena and manifested itself as a key player in the differentiation process of maxillofacial tumors.

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[Salma Belal Eiid, Mohamed Khalifa Zayet and Mushira Mohamed Dahaba. (2017); MAGNETIC RESONANCE SPECTROSCOPY AND THE METABOLIC FINGERPRINT OF MALIGNANT MAXILLOFACIAL TUMORS.A DIAGNOSTIC ACCURACY STUDY. Int. J. of Adv. Res. 5 (May). 622-629] (ISSN 2320-5407). www.journalijar.com

Salma Belal Eiid
Assistant lecturer of Oral and Maxillofacial Radiology, Faculty of Oral and Dental Medicine, Cairo University; Cairo, Egypt.

DOI:

Article DOI: 10.21474/IJAR01/4155      
DOI URL: https://dx.doi.org/10.21474/IJAR01/4155

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