Physiological and hematological changes in patients with chronic renal failure undergoing hemodialysis

In this study , 79 patients ( 54 males and 25 females ) suffering from chronic renal failure who were obtained from AL-Hakeem Hospital, AN Najaf, Iraq, and 79 healthy individuals were included as control group . The sera were separated from samples of patients blood and subjected to physiological investigation. We found that renal failure was more predominant among the patients ages group ranging from 19 – 60 years old. The results shows a significant increase in iron, ferritin and TIBC levels in CRF patients in both males (P<0.05) and females (P<0.05) but UIBC levels a significant increase in both males (P<0.05) and females (P<0.05) in (CRF) patients as compared with their control groups, furthermore no significant changing in (TS%) levels in both males (P>0.05) and females (P>0.05) in (CRF) patients as compared with their corresponding control groups , in addition to that a significant change in transferring levels in both males and females (P<0.05) (CRF) patients as compared with their parallel control. Then we subjected this sample to hematological studies and we found a significant decrease in (Hemoglobin) level s and (PCV) in both males and females (P<0.05) in (CRF) patients as compared with their corresponding control groups.