MICROWAVE IRRADIATION SYNTHESIS AND ANTIOXIDANT ACTIVITY OF ISATIN-OXADIAZOLE DERIVATIVES.

  • University College of Technology, Osmania University, Hyderabad-500007, T.S.
  • Department of Chemical Sciences, Osmania University, Hyderabad-500007, T.S.
  • Dept of Chemical Engineering, School of Mechanical, Chemical and Materials Engineering, Adama Science and Technology University, Adama, Ethiopia.
  • Centre for Pharmaceutical Sciences, Institute of Science and Technology, JNTUH.
  • Department of Pharmacy, Anurag Group Of Institutions,Venkatapur, Medchal, Hyderabad.
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Based on the literature review, we have found that Isatin- Oxadiazole derivatives are exhibiting different activities like anti-oxidant, anti-viral, anti-microbial and anti-convulsant and we synthesized Isatin-Oxadiazole hybrids. Among the series of compounds (E)-5-chloro-3,(2,(5-mercapto-1,3,4-oxadiazol-2yl)hydrazono)-indolin-2-one(IVb), (E)-5-bromo-3,(2,(5-mercapto-1,3,4-oxadiazol-2-yl)hydrazono)-indolin-2-one(IVe) showed most significant antioxidant activity.

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[K.Rama Devi, K.S.K Rao Patnaik, D. Ashok, Vasudha Bakshi, Raju Bathula and Satla Shobha Rani. (2017); MICROWAVE IRRADIATION SYNTHESIS AND ANTIOXIDANT ACTIVITY OF ISATIN-OXADIAZOLE DERIVATIVES. Int. J. of Adv. Res. 5 (Jun). 2329-2336] (ISSN 2320-5407). www.journalijar.com

K. RAMA DEVI
University College of Technology, Osmania University,Hyderabad-500007, T.S.

DOI:

Article DOI: 10.21474/IJAR01/4676      
DOI URL: https://dx.doi.org/10.21474/IJAR01/4676

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