29Aug 2017

SYSTEMIC MARKERS AND SURVIVAL OF ORAL CANCER PATIENTS IN EGYPT.

  • Senior Teaching Assistant, Oral Medicine, Periodontology, Oral Diagnosis and Radiology Dept., Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
  • Professor of Hematology, Clinical Pathology Dept., Faculty of Medicine, Mansoura University, Mansoura, Egypt.
  • Professor of Surgical Oncology, Oncology Center Mansoura University (OCMU), Faculty of Medicine, Mansoura University, Mansoura, Egypt.
  • Professor, Oral Medicine, Periodontology, Oral Diagnosis and Radioloy Dept., Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
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Background: Oral cancer is a common head and neck malignancy with poor survival rate specially with late diagnosis. Systemic markers have been shown to have a prognostic role in many cancers. The aim of the present study is to investigate the prognostic value of pretreatment systemic markers in a small group of oral caner patients in Egypt as a pilot study. Methodology: Twenty (20) oral cancer patients have been enrolled for the study. The systemic markers were assessed in relation with overall survival and recurrence free survival. Results: Neutrophils count (NC), neutrophils to lymphocytes ration (NLR) and platelets to lymphocytes ratio (PLR) were higher in dead patients compared to survivors. PLR was higher in patients with recurrence compared to patients without. However, these differences were not statistically significant. Conclusions: Systemic markers may help in predicting the survival of oral cancer patients. Further studies with larger samples are needed to verify their role.

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[Nancy M. Sobeih, Solafa A. Elsharawy, Nazem M. Shams and Una Mohamed El-Shinnawi. (2017); SYSTEMIC MARKERS AND SURVIVAL OF ORAL CANCER PATIENTS IN EGYPT. Int. J. of Adv. Res. 5 (Aug). 1849-1856] (ISSN 2320-5407). www.journalijar.com

Nancy M. S. Hussein
Senior Teaching Assistant, Oral Medicine, Periodontology, Oral Diagnosis and Radiology Dept., Faculty of Dentistry, Mansoura University, Mansoura, Egypt.

DOI:

Article DOI: 10.21474/IJAR01/5251      
DOI URL: https://dx.doi.org/10.21474/IJAR01/5251

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