10Aug 2017

THEVETIA PERUVIANA: A MULTIPURPOSE MEDICINAL PLANT- A REVIEW.

  • Department of Biotechnology, School of Life and Applied Sciences, Baba Farid Institute of Technology, Dehradun, Uttarakhand, India.
  • School of Biotechnology, Maharaj Vinayak Global University, Jaipur, Rajasthan, India.
  • Dean Research, Swami Rama Himalayan University, Dehradun, Uttarakhand, India.
Crossref Cited-by Linking logo
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Plant based therapeutics play an important role in the public health care system of any nation. The plant Thevetia peruviana belongs to the family Apocynaceae. The plant have a significant place in traditional system of medicine of Central and South America and tropical Asia. A number of different classes of secondary metabolites are present in Thevetia peruviana including alkaloids, flavonoids, steroids, cardiac glycosides, terpenoids, tannins, saponins etc. Several researchers had identified various pharmacological activities in different parts of the plant viz. seeds, flowers, bark, fruits, leaves. This review covers detailed ethanopharmacology, toxicology and bioactivities of Thevetia peruviana.


  1. Alhashimi, S.K.M., Rashid, K.I., Saleh, G.S., Abdulhadi, A.M. and Taher, T.A. (2013): The anti-microbial activity of leaves and callus extracts of Thevetia peruviana in vitro. J Biotech Res Cen, 7: 10-15.
  2. Ellenhorn, M.J. and Barceloux (1988): Medical toxicology: diagnosis and treatment of human poisoning. Elsevier, San Diego.
  3. Gogoi, N. and Bhuyan, B. (2017): In vivo antidiabetic activity evaluation of the bark of Cascabela thevetia in streptozotocin induced diabetic rats. Int J Pharm Pharm Sci, 9: 48-53.
  4. Gupta, R., Kachhawa J.B.S., Gupta, R.S., Sharma, A.K., Sharma, M.C. and Dobhal, M.P. (2011): Phytochemical evaluation and antispermatogenic activity of Thevetia peruviana methanol extract in male albino rats. Hum Fertil, 14: 53-59.
  5. Haldar, S., Karmakar, I., Chakraborty, M., Ahmad, D. and Haldar, P.K. (2015): Antitumor potential of Thevetia peruviana on Ehrlich?s Ascites Carcinoma ? Bearing Mice. J Environ Pathol Toxicol Oncol, DOI: 10.1615/J Environ Pathol Toxicol Oncol.2015012017.
  6. Mathuravalli, K. and Eswara, R.L. (2012): Analysis of phytochemical components and anti-microbial activity of the toxic plant Thevetia peruviana. Ind J Inn Dev, 1: 97-101.
  7. Miyagawa, T., Ohtsuki, T., Koyano, T., Kowithayakorn, T. and Ishibashi, M. (2009): Cardenolide glycosides of Thevetia peruviana and triterpenoid saponins of Sapindus emarginatus as TRAIL resistance overcoming compounds. J Nat Prod, 72: 1507-11.
  8. Nesy, E.A. and Mathew, L. (2016): In vitro cytotoxicity and anti-microbial efficacy of Thevetia peruviana seed kernel extracts. Int J Pharm Pharm Sci, 8: 47-50.
  9. Nesy, E.A., and Mathew, L.A. (2014): Comparative evaluation of anti-microbial and anti-oxidant properties of Thevetia neriifolia juss fruit rind extracts. Int J Curr Pharm Res, 6: 47-50.
  10. Oji, O. and Okafor, Q.E. (2000): Toxicological studies on stem bark, leaf and seed kernel of yellow oleander (Thevetia peruviana). Phytother Res, 14: 133-135.
  11. Reddy, B.U. (2010): Anti-microbial activity of Thevetia peruviana (Pers.) K. Schum. and Nerium Indicum Linn. Internet J Pharmacol, 8: 2.
  12. Sathish, V., Umavathi, S., Thangam, Y. and Mathivanan, R. (2015): Analysis of phytochemical components and larvicidal activity of Thevetia peruviana against the chickungunya vector Aedes aegypti (L). Int J Curr Microbiol Appl Sci, 4: 33-39.
  13. Singh, S.K., Yadav, R.P. and Singh, A. (2010): Piscicidal activity of leaf and bark extract of Thevetia peruviana plant and their biochemical stress response on fish metabolism. Eur Rev Med Pharmacol Sci, 14: 915-923.
  14. Theurkar, S.V., Patil, S.B., Ghadage, M.K., Birhade, D.N. and Gaikwad, A.N. (2014): Investigation on effect of Thevetia peruviana (Pers.) on the mortality of Holotrichia serrata (Fab.) adults (Coleoptera: Scarabaiedae). Int Res J Pharm, 5: 212-214.
  15. Yadav, S., Singh, S.P. and Mittal P.K. (2013): Toxicity of Thevetia peruviana (yellow oleander) against larvae of Anopheles stephensi and Aedes aegypti vectors of malaria and dengue. J Entomol Zool Stud, 1: 85-87.

[Tabrez Ahmad, Abdulhamid Tahir Hamid, Anuradha Sharma and Uma Bhardwaj. (2017); THEVETIA PERUVIANA: A MULTIPURPOSE MEDICINAL PLANT- A REVIEW. Int. J. of Adv. Res. 5 (Aug). 486-493] (ISSN 2320-5407). www.journalijar.com


Tabrez Ahmad
Deptt. of Biotechnology, School of Life and Applied Sciences, Baba Farid Institute of Technology, Dehradun, Uttarakhand, India

DOI:


Article DOI: 10.21474/IJAR01/5081      
DOI URL: http://dx.doi.org/10.21474/IJAR01/5081