20Oct 2017

CHOROIDAL METASTASIS INDICATIVE OF DISSEMINATED BRONCHOPULMONARY CANCER: TWO CASES.

  • Respiratory Diseases Department, ?20 Aout 1953? Hospital, Casablanca, Morocco.
Crossref Cited-by Linking logo

  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Introduction: ocular metastases are not common in bronchopulmonary cancers, and rarely inaugural. Observation: we report two cases of symptomatic choroidal metastasis, inaugural of bronchial carcinoma, in two patients aged 38 and 33 years old, respectively. The revealing signs are metamorphosis associated with a sharp drop in visual acuity. The histological type of the primary cancer is a slightly differentiated adenocarcinoma in the first case and a small cell carcinoma in the second case, respectively. An extended checkup confirmed the existence of liver and bone metastases in the first patient and the existence of adrenal metastases in the second patient. The evolution of these two cases has been marked by the death of both patients. Conclusion: ocular metastases may be inaugural of bronchial cancer and are often associated with other secondary locations. Starting early treatment could improve the visual prognosis of patients. However, the overall prognosis remains poor.

  1. Zografos L. M?tastasesintraoculaires. In: Tumeursintraoculaires. Chapitre 10. Masson; 2002. p. 381?412
  2. Kreusel KM,?Bornfeld N,?Hosten N,?Wiegel T,?Foerster MH. Solitary?choroidal?metastasis as the first sign of metastatic lung carcinoid. Arch Ophthalmol.1998 Oct;116(10):1396-7
  3. Shields CL, Shields JA, Gross NE, Schwartz GP, Lally SE. Survey of 520 eyes with uveal metastases. Ophthalmology 1997;104:1265?76
  4. Kreusel KM,?Wiegel T,?Stange M,?Bornfeld N,?Hinkelbein W,?Foerster MH . Choroidal?metastasis?in?disseminated?lung cancer: frequency and risk factors .Am J Ophthalmol.?2002 Sep;134(3):445-7
  1. Assouline P, Bussiere A, Thiellet A, Humbert M, Oliviero G. M?tastaseschoro?diennes des cancers bronchopulmonaires. Rev Mal Respir 2004;21:1153?6.
  2. Bloch RS, Gartner S?: The incidence of ocular metastatic carcinoma.?Arch Ophtalmol?1971?; 85?: 673-65.
  3. Nelson CC, Hertzberg BS, KlintworthGK?: A histopathologic study of 716 unselected eyes in patients with cancer at the time of death.?Am J Ophtalmol?1983?; 95?: 788-93.
  4. Kreusel KM, Bornfeld N, Hosten N, Wiegel T, Foerster MH?: Solitary choroidal metastasis as the first sign of metastatic lung carcino?d.?Arch Ophtalmol?1988?; 116?: 1396-7.
  5. http://www.ophtalmologieconferences.ca/crus/ophtfr_111205.pdf
  6. Tsina EK, Lane AM, Zacks DN, Munzenrider JE, Collier JM, Gragoudas ES. Treatment of metastatic tumors of the choroid with proton beam irradiation. Ophthalmology 2005;112:337?43.
  7. Shields CL, Shields JA, Gross NE, Schwartz GP, Lally SE. Survey of 520 eyes with uveal metastases. Ophthalmology 1997;104:1265?76.
  8. Wiegel T, Bottke D, Krensel KM, Schmidt S, Bornfeld N, Foerster MH, et al. External beam radiotherapy of choroidal metastases. Final results of a prospective study of the German Cancer Society (ARO 95-08). RadiotherOncol 2002;64:13?8
  9. Battikh MH, Ben Yahia S, Ben Sayah MM, Maatallah A, Joobeur S, Rouatbi N, et al. M?tastaseschoro?diennesr?v?latrices d?un ad?nocarcinomebronchique et involuant sous chimioth?rapie. RevPneumolClin 2004;60:353?6,

[Hind Janah, Meriem Choubi, Hasna Jabri, Wiam El Khattabi and Hicham Afif. (2017); CHOROIDAL METASTASIS INDICATIVE OF DISSEMINATED BRONCHOPULMONARY CANCER: TWO CASES. Int. J. of Adv. Res. 5 (Oct). 960-964] (ISSN 2320-5407). www.journalijar.com

Hind Janah
Respiratory Diseases Department, “20 Aout 1953” Hospital, Casablanca, Morocco

DOI:

Article DOI: 10.21474/IJAR01/5610      
DOI URL: https://dx.doi.org/10.21474/IJAR01/5610

Download Full Paper

Download PDF No. of Downloads: 2 | No. of Views: 53