SYSTEMIC ANTIBIOTIC PRESCRIPTION PATTERN IN NATIONAL GUARD OUTPATIENT CLINICS, JEDDAH, SAUDI ARABIA.
- King Saud bin Abdulaziz University for Health Sciences ? Jeddah, Saudi Arabia.
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Abstract
Background and Aim: Antibiotics are one of the most prescribed medications worldwide. The misuse of antibiotics is an international health issue that has led to the emergence of antibiotics resistance. The inappropriate prescription of antibiotics plays a major role in the development of microbial resistance. The aim of this study is to evaluate the pattern and extent of antibiotic prescription in outpatient clinics, King Abdulaziz Medical City (KAMC), National Guard Hospital? Jeddah, Saudi Arabia.
Methods: A total of 5472 prescriptions were reviewed on average of 240 prescriptions per day from 28th of January to 29th of February 2016. Prescriptions containing systemic antibiotics were analyzed for the main elements of medication order. The World Health Organization (WHO) core drug use indicators were measured.
Results: The percentage of prescriptions that contained systemic antibiotics was 8.2% (n=449) out of all prescriptions reviewed during the study period. Only 8% (n=36) of prescriptions contained more than one antibiotic agent, while the majority had single antibiotic. Family medicine clinics constituted 37% (n=168) of all prescribed antibiotics. The diagnosis was missing in 8.5% (n=38) of prescriptions. Allergy was not documented in 6.2% (n=28) of prescriptions. Upper respiratory tract disease (URTI) was the most common diagnosis in 35.6% (n=160) of patients who received antibiotics. The most frequently prescribed antibiotics were Augmentin and Azithromycin in 21.1% (n=95) and 20.7% (n=93) of patients, respectively.
Conclusion: The percentage of systemic antibiotic prescriptions in KAMC outpatient clinics was acceptable according to the WHO indicators. However, the missing information in some of prescription forms necessitates further monitoring and education on the rationale of antibiotics prescription.
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References
- Aminov RI. A brief history of the antibiotic era: lessons learned and challenges for the future. Front Microbiol. 2010;1:134.
- Goodman LS, Gilman A, Brunton LL. Goodman & Gilman's manual of pharmacology and therapeutics. New York: McGraw-Hill Medical; 2008. ix, 1219 p. p.
- Bergman M, Huikko S, Huovinen P, Paakkari P, Sepp?l? H, Renkonen R, et al. Macrolide and azithromycin use are linked to increased macrolide resistance in Streptococcus pneumoniae. Antimicrobial agents and chemotherapy. 2006;50(11):3646-50.
- Al-Niemat SI, Aljbouri TM, Goussous LS, Efaishat RA, Salah RK. Antibiotic prescribing patterns in outpatient emergency clinics at Queen Rania Al Abdullah II Children's Hospital, Jordan, 2013. Oman medical journal. 2014;29(4):250.
- Hicks LA, Bartoces MG, Roberts RM, Suda KJ, Hunkler RJ, Taylor TH, et al. US outpatient antibiotic prescribing variation according to geography, patient population, and provider specialty in 2011. Clinical Infectious Diseases. 2015:civ076.
- Oqal M, Elmorsy S, Alfhmy A, Alhadhrami R, Ekram R, Althobaiti I, et al. Patterns of antibiotic prescriptions in the outpatient department and emergency room at a Tertiary Care Center in Saudi Arabia. Saudi Journal of Medicine and Medical Sciences. 2015;3(2):124-9.
- Eldalo AS. Drug Prescribing Pattern among Physicians in an Outpatient Department of Tertiary Hospital, KSA. British Journal of Pharmaceutical Research. 2015;5(2):117.
- Irshaid YM, Al-Homrany MA, Hamdi AA, Adjepon-Yamoah KK, Mahfouz AA. A pharmacoepidemiological study of prescription pattern in outpatient clinics in Southwestern Saudi Arabia. Saudi medical journal. 2004;25(12):1864-70.
- Zowawi HM. Antimicrobial resistance in Saudi Arabia: An urgent call for an immediate action. Saudi Medical Journal. 2016;37(9):935-40.
- Al-Obeid S, Jabri L, Al-Agamy M, Al-Omari A, Shibl A. Epidemiology of extensive drug resistant Acinetobacter baumannii (XDRAB) at Security Forces Hospital (SFH) in Kingdom of Saudi Arabia (KSA). Journal of Chemotherapy. 2015;27(3):156-62.
- Shibl AM, Memish ZA, Kambal AM, Ohaly YA, Ishaq A, Senok AC, et al. National surveillance of antimicrobial resistance among Gram-positive bacteria in Saudi Arabia. Journal of Chemotherapy. 2014;26(1):13-8.
- Thong BYH, Tan TC. Epidemiology and risk factors for drug allergy. British journal of clinical pharmacology. 2011;71(5):684-700.
- Leekha S, Terrell CL, Edson RS. General Principles of Antimicrobial Therapy. Mayo Clinic Proceedings. 2011;86(2):156-67.
- el Moussaoui R, de Borgie CAJM, van den Broek P, Hustinx WN, Bresser P, van den Berk GEL, et al. Effectiveness of discontinuing antibiotic treatment after three days versus eight days in mild to moderate-severe community acquired pneumonia: randomised, double blind study. BMJ : British Medical Journal. 2006;332(7554):1355-.
- Shapiro DJ, Hicks LA, Pavia AT, Hersh AL. Antibiotic prescribing for adults in ambulatory care in the USA, 2007?09. Journal of Antimicrobial Chemotherapy. 2013:dkt301.
- Control CfD, Prevention. Outpatient antibiotic prescriptions?United States, 2013. Available; 2016. p. 203.
How to Cite This Article
Abdulaziz Abdulnasir Aldahlawi, Samer Abdulmoghny Alamri, Ahmed Mohammed Alfaidi and Mohammed Abdullah Babgi. (2018); SYSTEMIC ANTIBIOTIC PRESCRIPTION PATTERN IN NATIONAL GUARD OUTPATIENT CLINICS, JEDDAH, SAUDI ARABIA., Int. J. of Adv. Res., 6 (02), 37-41, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/6405
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