REVIEW OF INCIDENCE OF CARCINOID LUNG TUMORS IN IRAQ.

  • FIBMS(th.c.v.s)PACs.,MRcs.,FRCS(Glasgow).professor and consultant of cardiothoracic and vascular surgeon.chairman of the scientific Council of thoracicand cardiovascular surgery.
  • MBCHB.FICMS cardiothoracic and vascular surgeon.
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Background: Carcinoid lung tumors are rare tumor which tend to be slow growing. They are one type of neuroendocrine tumors, they have two type, typical (low grade) and atypical (intermediate grade). 1.2% of primary lung tumors are carcinoid. The average age of people affected is 40-50 years for typical subtype while atypical have been reported in virtually every age group. Cough, dyspnea, hemoptysis and recurrent chest infection are the main presenting symptoms. Chest x-ray, CT scan of chest and bronchoscopy are the main tools in the diagnosis of carcinoid lung tumor. Management was mainly surgical with resection of the affected lobe or lobes of the lung obiective: the study is planned to review the incidence of carcinoid lung tumor, methods of diagnosis and outcome of surgical treatment. Study design: retrospective and comparative study Setting: Department of Thoracic Surgery of Al-shaheed Ghazi hariri Hospital, Medical City Teaching Complex, Baghdad, Iraq Patients and methods: review of clinical record and surgeon note of 20-patients with carcinoid lung tumor during 18-years (1996-2013). Collecting information relevant to patients variable with regard to age, sex, presenting symptoms, radiographic findings (chest x-ray and CT scan) bronchoscopic finding, pre-operative preparation, post-operative course and the histopathology of the resected specimens. Results: 13 patients out of 20 (65%), were under the age of 40 year. 11 patients out of 20 (55%) were female. Cough and shortness of breath are the most common presenting symptoms. All of patients have a typical bronchoscopic findings with cherry-red-coloured, smooth, polypoid, vascular tumor that bleeds easily and profusely. All the patients were managed surgically with formal postero lateral thoracotomy and resection of affected part of lung and there was no significant post-operative complication. conclusion: Early detection of bronchial carcinoid tumor with the use of Endobronchial ultra Sound EUs or future tumor markers, a more conservative surgical procedure such as sleeve or wedge resection, can be adopted with the hope of saving more functioning lung tissue.


1. http://m.cancer.org/cancer/lungcarcinoidtumor/detaileguide/lung-carcinoid-tumor-what -is-lung carcinoid-tumor. 2. Waleed M. Hussen, Abdulameer M. Hussein. Carcinoid lung tumor. The Egyptian Journal of Surgery 2014:33:160-163 . 3. Chong S, Lee KS, Chung MJ. Neuroendocrine tumors of the lung: clinical, pathologic, and imaging findings. Radiographics. Jan Feb 2006,26(1):41-57; discussion 57-8 . 4. Frank Sellke, Pedro J. Nid, Scott Swanson. Sabiston and spencer's Surgery of chest 8TH edition 2010 22(2):323-28. 5- Rusch VW, Klimstra DC, Venkatraman ES. Molecular markers help characterize neuroendocrine lung tumors. Ann thoracic surgery. 1996:62:798-810 . 5. Meisinger QC, Klein US, Butnor KJ, Gentchos G. Leavitt Bj. CT Features of Peripheral Pulmonary Carcinoid Tumors. AJR Am JRoentgenol. Nov 2010.197(5):1073-80 . 6. Hande KR in Goldman L, Schafer AL, eds Carcinoid syndrome. Cecil medicine. 24TH ed Philadelphia, PA: Saunders Elsevier, 2011. 7. Meade RH. Tumors and cysts of the lung. In: A History of Thoracic Surgery. Springfield, Ill Charles C. Thomas; 1961:175-222. 8. E.Goljan, Rapid review pathology, 2nd ed. Tulsa, oklahoma, USA: Mosby Elsevier. 10. Cote ML, Wenzlaff AS, Philip PA, Schwartz AG. Secondary cancers after a lung carcinoid primary: a population-based analysis. Lung Cancer. Jun 2006;52(3):273-9 9. Choman S. Omer. Chest x-ray made easy.2009;3:27-64 10. M. Bakhshyesh Karam, S. Zahirfad, M.O. Tahbaz, K. Kaynama, F. Tolau, H.Jabari Darjani et al. Bronchial carcinoid tumors clinical and radiological study. Iran J. Radiol. June 2005:2(3,4):111-16 . 11. Guckel C, Schnabel K, Deimling M. Solitary pulmonary nodules: MR re-evaluation of enhancement patterns with contrast-enhanced dynamic snapshot gradient-echo imaging. Radiology. 1996;200:681-86 . 12. Jindal T, Kumar A, Venkitaraman B, Meena M, Kumar R, Malhorta A, et al. evaluation of the role of [18FlFDG PET/CT and 168GalDOTATOC-PET/CT in differentiating typical and atypical pulmonary carcinoids. Cancer imaging. Jun 15 2011 11:70-5 . 13. Esfahani AF, Chavoshi M, Noorani MH, Saghari M, Eftekhari M,Beiki D, et al. succeful application of technetium-99m-labeled octreotide acetate scintigraphy in the detection of ectopic adrenocorticotropin-producing bronchial carcinoid lung tumor: a case report. J Med Case Reports. Oct 18 2010,4 323 . 14. Hubalewska-Dydejczyk A, Fross-Baron K, Mikolajczak R. (99m)Tc-EDDA/HYNIC-octreotate scintigraphy, an efficient method for the detection and staging of carcinoid tumours: result of 3 years' experience. Eur J Nucl Med Mol Imaging. 2006. 15. MusiM, Carbone RG, Bertocchi c Branchial carcinoid tumours: a study on clinicopathological features and role of octreotide scintigraphy, Lung cancer 1998 2297. 102. 16. Yendamuri S. Gold D, Jayaprakash V, Dexter E. Nwogu C, Demmy T. Is sublobar Resection sufficient for carcinoid Tumors? Ann Thorac Surg. Jun 23 2011. 17. Tastepe Al. Kurul IC, Demircan S. long-term survival following bronchotomy for polypoid bronchial carcinoid tumours. European Jornal of Cardio-thoracic surgery 1998 14:575-577. 18. Chughtai TS, Morin JE, Sheiner NM, Wilson JA, Mulder Ds. Bronchial carcinoid- twenty years' experience defines a selective surgical approach. Surgery, Oct 1997;12204) 801-8. 19. Lemaitre J Mansour Z, Kochetkova EA, Koriche C. Ducrocq x, Wihlm JM, Bronchoplastic lobectomy: do early results depend on the underlying pathology A comparison between typical carcinoids and primary lung cancer. Eur J Cardiothorac Surg Jan 2006;3001:168- 71. 20. Ducrocq x, Thomas P, Massard G. operative risk and prognostic factors of typical bronchial carcinoid tumors. Ann Thorac Surg. 1998:65:1410-4 . 21. Harpole DH Jr, Feldman JM, Buchanan S. Bronchial carcinoid tumors: a retrospective analysis of 126 patients. Ann Thorac Surg. Jul 1992;s4f1:50-4 discussion 54-5. 22. Rea F. Binda R, Spreafico G. bronchial carcinoids: areview of 60 patients. Ann Thorac Surg Mar 1989:47 (3):412-4 . 23. Modlin IM, Lye KD, Kidd MA 5 decade analysis of 13.715 carcinoid tumor. Cancer 2003.934-59 . 24. TAkiba, T Naruke. H Kondo, et al:carcinoid tumor of the lungciincopathological study of 32 cases, Jpn J Clin Oncol 1992;22:92-95 . 25. Paladugu RR, Benfield JR, Pak HY, et al. Bronchopulmonary Kulchitzky cells carcinomas: a new classification scheme for typical and atypical carcinoid cancer.1985;55:1303-11. 26. Hamid RJ, Kian KH, Ali D, et al: pulmonary carcinoid tumor, Tanaffos 2002;1:51-56. 27. Todd TR, Cooper JD, Weissberg D, et al. Bronchial carcinoid tumors: twenty years experience. JThoracic Cardiovasc Surg 1980 79:532-35 . 28. Ronchod M, Levine GD Spindle-cell carcinoid tumors of the lung: a clinicopathological study of 35 cases. Am U Surg Pathol 1980 4:315-30 . 29. Ismail C, Salih T, Irfan et al. Surgery in bronchial carcinoid: experience with 83 patients Eur J Cardiothoracic Surg 2002 21:883-887 . 30. Elhassani NB: Bronchial carcinoid tumors, Ann Saudi med 1988 8:35.

[waleed M. hussein M. S, Abdul-Razzaq N. Rashied and sadoon. H. Al-Hayazie. (2018); REVIEW OF INCIDENCE OF CARCINOID LUNG TUMORS IN IRAQ. Int. J. of Adv. Res. 6 (Feb). 1802-1808] (ISSN 2320-5407). www.journalijar.com


Dr .sadoon .H.Al-Hayazie,MBCHB,FICMS cardiothoracic and vasc
Al Yarmuk teaching hospital,Baghdad,Iraq.

DOI:


Article DOI: 10.21474/IJAR01/6620      
DOI URL: https://dx.doi.org/10.21474/IJAR01/6620