28Mar 2018

COMPARISON OF THE HEALING POTENTIAL OF PROPOLIS AND BEE VENOM ON SURGICALLY INDUCED WOUND IN RAT?S BUCCAL MUCOSA.

  • Oral Biology Department, Faculty of Dentistry, Modern Sciences and Arts University (MSA), Egypt.
  • Oral Biology Department, Faculty of Oral and Dental Medicine, Cairo University, Egypt.
  • Oral Biology Department, Faculty of Oral and Dental Medicine, Cairo University, Egypt.
  • Oral Biology Department, Faculty of Oral and Dental Medicine Cairo University, Egypt.
  • Microbiology and Immunology, National Research Center, Egypt.
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Bee products include honey as well as propolis, royal jelly and venom which are used in medicine, not only as an immune system stimulant but also as a wound healing promoter. Aim of work: was to assess and compare the healing potential of propolis and bee venom on the healing wounds in rat?s buccal mucosa. Materials and Methods: Foutry five adult male Wistar albino rats divided into in 3 groups of 15 each (control, propolis & bee venom). A wound (3.5 mm diameter) was made in the cheek of each rat with a punch biopsy. Samples were prepared and investigated histopathologically and immunohistochemically by proliferating cell nuclear antigen (PCNA) after 1, 3 and 7 days of wounding. Results: Bee venom showed the highest healing potential followed by propolis through stimulated epithelial cells proliferation and reepithelization compared to the control group. Conclusion: Bee venom and Propolis had contributed positively to the wound healing in the surgically induced wounds of rat?s buccal mucosa.

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[Lina Samir Shalaby, Ahmed Helmy Salama, Sahar Mahmoud Shawkat, Amira Elham Fares and Ahmed Gaafar Hegazi. (2018); COMPARISON OF THE HEALING POTENTIAL OF PROPOLIS AND BEE VENOM ON SURGICALLY INDUCED WOUND IN RAT?S BUCCAL MUCOSA. Int. J. of Adv. Res. 6 (Mar). 1268-1275] (ISSN 2320-5407). www.journalijar.com

Lina Samir Shalaby
Egyptian

DOI:

Article DOI: 10.21474/IJAR01/6795      
DOI URL: https://dx.doi.org/10.21474/IJAR01/6795

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