15Apr 2018

AWARENESS AND CORRELATION BETWEEN SOME FACTORS SUCH AS IRON DEFICIENCY ANEMIA, OBESITY & HYPERLIPIDEMIA, IN HYPOTHYROIDISM PATIENTS IN HAIL, KINGDOM OF SAUDI ARABIA.

  • Department of Pediatrics, College of Medicine, Hail University, KSA.
  • College of Medicine, Hail University, KSA.
Crossref Cited-by Linking logo

  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Background: Hypothyroidism is a common endocrinal disorder in which thyroid gland does not produce enough thyroid hormones. A lot of diseases may be the underlying cause of Hypothyroidism. In this research we will see the awareness and correlation between some factors such as Iron deficiency anemia, obesity & hyperlipidemia, in Hypothyroidism patients in Hail, Kingdom of Saudi Arabia. Aims and Objectives: We aimed to describe the changing incidence and prevalence of thyroid disease in Hail, Kingdom of Saudi Arabia and to evaluate if there is any significant correlation between some factors such as Iron deficiency anemia, hyperlipidemia, and Hypothyroidism. Methodology: The data was carried out on 800 Saudi participant from Hail, Kingdom of Saudi Arabia by handling out questionnaires. Results: The data showed 168 (21%) are thyroid gland patients out of 800 people. Among the 168 patients there were 142 (17.75%) hypothyroidism patients. These patient were either overweight or obese, others with iron deficiency were 52 (36.62%) and with hyperlipidemia were 49 (34.51%). Conclusion: The current study have a significant role for the future incidence of hypothyroidism in Hail, Kingdom of Saudi Arabia, and for the health providers they should start increasing the awareness about the thyroid and it?s diseases. We also showed that the prevalence of anemia is high in hypothyroidism, also the TSH measurement should be routinely recommended in the initial work-up of anemia.

  1. Madariaga AG, Palacios SS, Guill?n-Grima F, Galofr? J (2014). The incidence and prevalence of thyroid dysfunction in Europe: a meta-analysis. J Clin Endocrinol Metab 99: 923-931.
  2. Kumar V, Abbas AK, Mitchell RN, Fausto N (2007). Robbins basic pathology (8th edn.) United States.
  3. Velayutham K, Selvan S, Unnikrishnan A (2015). Prevalence of thyroid dysfunction among young females in a South Indian population. Indian J Endocrinol Metab 19: 781-784.
  4. Moussa D, Alshammari A, Alshammari G, Alshammari K, Alanzi M, Alanzi N, and Alshammari Z (2016). Pattern of Thyroid Disease in Hail Region, Saudi Arabia. J. Adv. Res., 4 (9), 1235?1246.
  5. Rabet-Bensalah K M, Aubert CE, Coslovsky M, Collet TH, Baumgartner C, Den Elzen WPJ, R. Luben, Angelillo-Scherrer A, Aujesky D, Khaw KT, and Rodondi N( 2016). Thyroid dysfunction and anaemia in a large population-based study. Endocrinol. (Oxf), 84 (4), 627?631.
  6. BRIEN O, DINNEEN SF, BRIEN PCO, and PALUMBO PJ (1993). Hyperlipidemia in Patients with Primary and Secondary Hypothyroidism. Mayo Clin. Proc., vol. 68(9), 860?866.
  7. Lee GR, Foerster J, Lukens J, et al. (1999). Anemia: a diagnostic In: Greer JP, Forester J, Rogers GM, et al. Wintrobe?s Clinical Hematology, 10th edn. Williams & Wilkins, Baltimore, Philadelphia, 908?940.
  8. Colon-Otero G, Menke D & Hook CC (1992). A practical approach to the differential diagnosis and evaluation of the adult patient with macrocytic anemia. Medical Clinics of North America,76, 581?597.
  9. Kaferle J & Strzoda CE (2009). Evaluation of macrocytosis. American Family Physician, 79, 203?208.
  10. Jason WH, Stephen FH, Rajasehkar R, Govind B, Peter HRG (2007). Anemia in celiac disease is multifactorial in etiology. Am J Hematol; 82: 996?1000.
  11. Sonja YH, Michael BZ, Myrtha A, Wolfgang L, Richard FH (2002). Iron deficiency anemia reduces thyroid peroxidase activity in rats.? J Nutrition; 132: 1951-1955.
  12. Shakir KM, Turton D, Aprill BS, Drake AJ, Eisold JF (2000). Anemia: a cause of intolerance to thyroxine sodium. Mayo Clinic Proceedings; 75: 189-192.
  13. Chen SCH, Shirazi MRS, Orr RA (1983). Triiodothyronine and thyroxine levels in iron deficient, hyper triglyceridemic rats. Nutr Res; 3: 91-106.
  14. Beard JL, Borel MJ, Deer J (1990). Impaired thermoregulation and thyroid function in iron deficiency anemia. Am J Clin Nutr; 52: 813-819.
  15. Jonathan SM, Rubaraj J, Petros P (2001). Deterioration of symptoms after start of thyroid hormone replacement.? Br Med J; 323: 332.
  16. Erdogan M, ?osenli K A, Ganidagli S, et al. (2012). Characteristics of anemia in subclinical and overt hypothyroid patients. Endocrine Journal, 59, 213?220.
  17. Duntas LH. (2002). Thyroid disease and lipids. Thyroid; 12: 287-93.
  18. Friis T, Pedersen LR (1987). Serum lipids in hyper- and hypothyroidism before and after treatment. Clin Chim Acta; 162: 155-63.
  19. Canaris GJ, Manowitz NR, Mayor G, Ridgway EC (2000). The Colorado thyroid disease prevalence study. Arch Intern Med; 160: 52634.
  20. Asvold BO, Vatten LJ, Nilsen TI, Bjoro T(2007). The association between TSH within the reference range and serum lipid concentrations in a population-based study. The HUNT Study. Eur J Endocrinol; 156: 181-6.
  21. Rizos CV, Elisaf MS and Liberopoulos EN (2014), ?Effects of thyroid dysfunction on lipid profile,? Open Cardiovasc. Med. J., vol. 5, pp. 76?84, 201.

[Mona Madbouly Shahin, Noura Saleh Dagafag Algrwan and Muradi Hisham Abdulaziz Algriys. (2018); AWARENESS AND CORRELATION BETWEEN SOME FACTORS SUCH AS IRON DEFICIENCY ANEMIA, OBESITY & HYPERLIPIDEMIA, IN HYPOTHYROIDISM PATIENTS IN HAIL, KINGDOM OF SAUDI ARABIA. Int. J. of Adv. Res. 6 (Apr). 875-879] (ISSN 2320-5407). www.journalijar.com

Mona Madbouly Mohammad Shahin
Department of Pediatrics, College of Medicine, Hail University, KSA.

DOI:

Article DOI: 10.21474/IJAR01/6923      
DOI URL: https://dx.doi.org/10.21474/IJAR01/6923

Download Full Paper

Download PDF No. of Downloads: 22 | No. of Views: 177