13Oct 2018

RISK FACTORS OF EARLY AND LATE ONSET PREECLAMPSIA IN SAMPLE OF IRAQI WOMEN.

  • Cabog ,Ficogobstetrics and gynecology departmentcollege of medicine / al-iraqiauniversity.
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Objective:The aim of this study was to identify the differences in risk factors between early and late onset pre-eclampsia in sample of Iraqi women. Material and methods:This retrospective study was carried out involving pregnancies with pre-eclampsia (65 early onset and 143 late onset) and 235 controls at different hospitals in Baghdad city between 1 January 2014 and 31 December 2017. The data were reviewed from antenatal and delivery records. Results:Factors which were significantly associated with increased risk for early onset pre-eclampsia were history of chronic hypertension and higher BMI before pregnancy while family history of chronic hypertension and increased maternal age was significantly associated with increased risk for only late onset pre-eclampsia. Previous history of preeclampsia, Nulliparity and family history of diabetes are associated with both early and late preeclampsia. Conclusions:Early- and late-onset preeclampsia may have the same etiological features but they differ with regard to several risk factors, and can lead to different outcomes, so they should be treated as distinct entities from an etiological and prognostic standpoint. Identification of the risk factors for each type is of value to obstetricians in recognizing patients at risk for pre-eclampsia and in implementing primary prevention.

  1. Kayode O. Osungbade1 and Olusimbo K. Ige. Public Health Perspectives of Preeclampsia in Developing Countries: Implication for Health System Strengthening. Journal of Pregnancy 2011 : 6 .
  2. Hutcheon JA, Lisonkova S, Joseph KS. Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy. Best Pract Res ClinObstetGynaecol. 2011 Aug;25(4):391-403.
  3. Cande V Ananth, Katherine M Keyes, Ronald J Wapner. Pre-eclampsia rates in the United States, 1980-2010: age-period-cohort analysis. BMJ 2013; 347 : f6564.
  4. Villar J, Say L, Gulmezoglu AM, Meraldi M, Lindheimer MD, Betran AP, Piaggio G; Eclampsia and pre-eclampsia: a health problem for 2000 years. In Pre-eclampsia, Critchly H, MacLean A, Poston L, Walker J, eds. London, RCOG Press, 2003, pp 189-207.
  5. Ronsmans C, Graham WJ on behalf of the Lancet Maternal Survival Series steering group, ?Maternal mortality; who, when, where and why.? The Lancet, Maternal Survival, September 2006.
  6. Maternal mortality in 2005: estimates developed by WHO, UNICEF, UNIFPA and the World Bank, Geneva, World Health Organization, 2007.
  7. Valensise H1, Vasapollo B, Gagliardi G, Novelli GP. Early and late preeclampsia: two different maternal hemodynamic states in the latent phase of the disease. Hypertension. 2008 Nov; 52(5): 873-80.
  8. Lisonkova S1, Joseph KS. Incidence of preeclampsia: risk factors and outcomes associated with early- versus late-onset disease. Am J Obstet Gynecol. 2013 Dec ; 209(6):544.e1-544.e12.
  9. Sibai BM, Caritis S, Hauth J. What we have learned about preeclampsia. SeminPerinatol. 2003;27(3):239?246.
  10. 1Lindheimer MD, Taler SJ, Cunningham FG. Hypertension in pregnancy. J Am SocHypertens. 2008;2(6):484?494.
  11. Valensise H, Vasapollo B, Gagliardi G, Novelli GP. Early and late preeclampsia: Two different maternal hemodynamic states in the latent phase of the disease. Hypertension. 2008;52(5):873?880.
  12. Judi A Turner. Diagnosis and management of pre-eclampsia: an update. Int J Womens Health. 2010; 2: 327?337.
  13. ACOG Committee on Obstetric Practice. ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002. American College of Obstetricians and Gynecologists.Int J Gynaecol Obstet. 2002 Apr;77(1):67-75.
  14. 1von Dadelszen P, Magee LA, Roberts JM.Subclassification of preeclampsia.Hypertens Pregnancy. 2003;22:143?8.
  15. Fang R, Dawson A, Lohsoonthorn V, Williams MA. Risk factors of early and late onset preeclampsia among Thai women.Asian Biomed (Res Rev News) 2009; 3: 477?486.
  16. Duckitt K, Harrington D. Risk factors for pre-eclampsia at antenatal booking: Systematic review of controlled studies. BMJ 2005; 330: 565?571.
  17. Nanjundan P, Bagga R, Kalra JK, Thakur JS, Raveendran A. Riskfactorsforearlyonsetseverepre-eclampsiaandeclampsia among north Indian women. J ObstetGynaecol 2011; 31: 384?389.
  18. Poon LC, Kametas NA, Chelemen T, Leal A, Nicolaides KH. Maternal risk factors for hypertensive disorders in pregnancy: A multivariate approach. J Hum Hypertens 2010; 24: 104?110.
  19. Takacs P, Kauma SW, Sholley MM, Walsh SW, Dinsmoor MJ, Green K. Increased circulating lipid peroxides in severe preeclampsia activate NF-kappaB and upregulate ICAM-1 in vascular endothelial cells. FASEB J 2001; 15: 279?281.
  20. Cheng MH, Wang PH. Placentation abnormalities in the pathophysiology of preeclampsia. Expert RevMolDiagn 2009; 9: 37?49.
  21. SarkaLisonkova, and K.S. Joseph. Incidence of preeclampsia: risk factors and outcomes associated with early- versus late-onset disease. AJOG 2013 ; 209, Issue 6: 544.e1?544.e12.
  22. AnmarAltaeiandJumahMasoud Mohammad. Incidence and Risk Factors of Pre-eclampsiaAmong Iraqi Pregnant women. AJPS 2012 ; 12 : 2: 52-60.

[Dalyathamer Ahmed. (2018); RISK FACTORS OF EARLY AND LATE ONSET PREECLAMPSIA IN SAMPLE OF IRAQI WOMEN. Int. J. of Adv. Res. 6 (Oct). 809-814] (ISSN 2320-5407). www.journalijar.com

Assistant Professor Dr.Dalya Thamer Ahmed

DOI:

Article DOI: 10.21474/IJAR01/7874      
DOI URL: https://dx.doi.org/10.21474/IJAR01/7874

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