16Oct 2018

RARE PRESENTATION OF AREOLAR SEBACEOUS HYPERPLASIA.

  • Faculty of Medicine, King Abdulaziz University, Saudi Arabia (Medical Intern).
  • Department of Dermatology, Faculty of Medicine, King Abdulaziz University, Saudi Arabia.
  • Abstract
  • References
  • Cite This Article as
  • Corresponding Author

A 56-year-old woman reported the appearance of a lesion in both breasts characterized by the presence of yellowish thickening of the areolae with the presence of papules and nodules. The mammography didn?t show an underlying malignant lesions and the biopsy concluded to Montgomery tubercles.


  1. Kanada KN, Merin MR, Munden A, Friedlander SF. A prospective study of cutaneous findings in newborns in the United States: correlation with race, ethnicity, and gestational status using updated classification and nomenclature. J Pediatr. 2012 Aug. 161(2):240-5.
  2. Moosavi Z, Hosseini T. One-year survey of cutaneous lesions in 1000 consecutive Iranian newborns. Pediatr Dermatol. 2006 Jan-Feb. 23(1):61-3
  3. Brzezinski P, Chiriac A. Sebaceous hyperplasia in neonates and adults. Our Dermatol Online. 2015;6(1):107-108.
  4. Engel F, Ellero B, Woehl-Jaegle ML, Cribier B. Diffuse sebaceous hyperplasia of the face induced by cyclosporine. Ann Dermatol Venereol. 2005 Apr;132(4):342-5.
  5. Sato T, Tanaka M.Linear sebaceous hyperplasia on the chest. Dermatol Pract Concept. 2014 Jan 31;4(1):93-5
  6. Roma AA, Barry J, Pai RK, Billings SD.Sebaceous hyperplasia of the vulva: a series of cases reporting no association with the Muir-Torre syndrome. Int J Gynecol Pathol. 2014 Jul;33(4):437-42.
  7. Lester RA, Torgerson RR, Sandhu NP. Rare presentation of sebaceous hyperplasia. BMJ Case Reports. 2014;2014:bcr2014204025. doi:10.1136/bcr-2014-204025.
  8. Zouboulis CC. Acne and sebaceous gland function. Clin Dermatol. 2004 Sep-Oct;22(5):360-6.
  9. Catalano PM, Ioannides G. Areolar sebaceous hyperplasia. J Am Acad Dermatol 1985;13:867?868.
  10. Krisp A, Krause W. Areolar sebaceous hyperplasia. Acta Derm Venereol. 2003;83:61?2.
  11. S?nchez Yus E, Montull C, Valcayo A, et al. Areolar sebaceous hyperplasia: a new entity?. J Cutan Pathol 1988;15:62?3.
  12. Hammerton MD, Shrank AB. Superficial sebaceous hyperplasia of the areolae. Br J Dermatol 1993;129:649?50.
  13. Tsuji T, Yamauchi R. Areolar sebaceous hyperplasia with a Fordyce?s spot-like lesion. J Dermatol 1994;21:524?6.
  14. Belinch?n I, Aguilar A, Tard?o J, et al. Areolar sebaceous hyperplasia: a case report. Cutis 1996;58:63?4.
  15. Fari?a MC, Soriano ML, Escalonilla P, et al. Unilateral areolar sebaceous hyperplasia in a male. Am J Dermatopathol 1996;18:417?19.
  16. Kondo-Morita A, Murata S, Murakami T, et al. Bilateral areolar sebaceous hyperplasia in a male. J Dermatol 2001;28:172?3.
  17. Bajaj V, Barrett P, Sripathy T, et al. Areolar sebaceous hyperplasia in a male: a different morphology. J Cutan Pathol 2007;34:207?8.
  18. Conde-Taboada A, De la Torre C, Mayo E, et al. Unilateral areolar sebaceous hyperplasia in a male. J Eur Acad Dermatol Venereol 2007;21:120?1.
  19. Guillermo N, Pe?ate Y, Soler E, et al. Bilateral areolar sebaceous hyperplasia in a female. Int J Dermatol 2008;47:1214?15.
  20. Tulbert B, Brodell RT. A simple and effective treatment for ectopic sebaceous glands on the areola. Dermatol Surg 2010;36:1332?5.
  21. Fernandez-Flores A, Valerdiz S, Crespo LG, et al. Areolar sebaceous hyperplasia with underlying primary duct carcinoma of the breast in a woman with Donohue syndrome (leprechaunism). Am J Dermatopathol 2012;34:e15?18.
  22. Errichetti E, Piccirillo A, Viola L, et al. Areolar sebaceous hyperplasia associated with oral and genital Fordyce spots. J Dermatol 2013;40:670.
  23. Zucca-Matthes G, Urban C,3 Vallejo A. Anatomy of the nipple and breast ducts. Gland Surg. 2016 Feb; 5(1): 32?36.
  24. Perkins OC, Miller AM. Sebaceous glands in the human nipple. Am J Obstet Gynecol 1926; 11: 789 ? 794
  25. Zouboulis CC, Boschnakow A. Chronological ageing and photoageing of the human sebaceous gland. Clin.Exp.Dermatol. 2001;26:600-7.
  26. Weisshaar E, Schramm M, Gollnick H. Familial nevoid sebaceous gland hyperplasia affecting three generations of a family. Eur J Dermatol. 1999;9:621-3.
  27. Kumar P, Marks R. Sebaceous gland hyperplasia and senile comedones: a prevalence study in elderly hospitalized patients. Br J Dermatol. 1987;117:231-6
  28. Pang SM, Chau YP. Cyclosporin-induced sebaceous hyperplasia in renal transplant patients.Ann Acad Med Singapore. 2005;34:391-3.
  29. Grillo E, P?rez-Gala S, Vano-Galv?n S, Ja?n-Olasolo P. Multiple sebaceous hyperplasia secondary to ciclosporin in a heart transplant patient. Med Clin (Barc) 2013; 141: e3.
  30. Blech H, Friebe K, Krause W. Inflammation of Montgomery Glands. Acta dermato-venereologica. 2004;( 84): 93-4.
  31. Tavassoli FA, Eusebi V. Tumors of the mammary gland. In: Silverberg SG, Gardner WA, Sobin LH, eds. AFIP Atlas of Tumor Pathology. 4th series, fascicle 10. Washington, DC: American Registry of Pathology, 2009; 8-10: 371-81.
  32. Requena L, Requena C. Gl?ndulasseb?ceas ect?picas: condici?n de Fordyce y corp?sculos de Montgomery. En: Neoplasiasanexialescut?neas, 2004: 375?380.
  33. Yost J, Robinson M, Meehan SA. Fox-Fordyce disease. Dermatol Online J. 2012 Dec 15;18(12):28.
  34. Gold MH, Bradshaw VL, Boring MM, Bridges TM, Biron JA, Lewis TL. Treatment of sebaceous gland hyperplasia by photodynamic therapy with 5-aminolevulinic acid and a blue light source or intense pulsed light source. J Drugs Dermatol. 2004;3:S6-S9.
  35. Tagliolatto S, Santos O de O, Alchorne MM de A, Enokihara MY. Sebaceous hyperplasia: systemic treatment with isotretinoin. Anais Brasileiros de Dermatologia. 2015;90(2):211-215. doi:10.1590/abd1806-4841.20153192.
  36. Papakonstantinou E, Aletras AJ, Glass E, Tsogas P, Dionyssopoulos A, Adjaye J,et al. Matrix metalloproteinases of epithelial origin in facial sebum of patients withacne and their regulation by isotretinoin. J Invest Dermatol. 2005 Oct;125:673-84.
  37. Fernandez-Flores A; Valerdiz S; Luis G. Crespo; Rodriguez-Cernuda P. Areolar Sebaceous Hyperplasia with Underlying Primary Duct Carcinoma of the Breast in a Woman with Donohue Syndrome (Leprechaunism). Am J Dermatopathol. 2012 Apr;34(2):e15-8.

[Reem H. Alenazi and Sara Qari. (2018); RARE PRESENTATION OF AREOLAR SEBACEOUS HYPERPLASIA. Int. J. of Adv. Res. 6 (Oct). 1206-1211] (ISSN 2320-5407). www.journalijar.com


Sara Qari
Department of Dermatology, Faculty of Medicine, King Abdulaziz University, Saudi Arabia.

DOI:


Article DOI: 10.21474/IJAR01/7924      
DOI URL: https://dx.doi.org/10.21474/IJAR01/7924