Vol. 6 (11) pp. 790-797 DOI: 10.21474/IJAR01/8060

GASTRIC MUCOSAL CHANGES IN DUODENAL SWITCH OPERATION IN MANAGEMENT OF MORBID OBESITY:PRE- AND POST-OPERATIVE COMPARISON.

, , , , and
12 Downloads 67 Views
Crossref

Download Full Paper (PDF)

Abstract

Objectives: Duodenal switch has proved to be the most effective procedure in management of morbid obesity as it has long-term weight loss outcome and co-morbidity improvement.It is important to study the types of abnormal histopathologic pattern in the gastric mucosa in patients with duodenal switch operation and follow up of those changes 6 month after the operation Methods: 25 morbidly obese patients were included in this study. All patients were treated in the Endocrine Surgery Unit (ESU), Mansoura University Hospitals. ِAll patients did duodenal switch operation ( single anastomosis duodeno-ileal bypass with sleeve gastrectomy) and a biopsy from their gastric mucosa was taken at the time of the operation.Follow up of those patient was done six month after surgery regarding body weight, body mass index, weight loss and a biopsy was taken by upper gastro-intestinal endoscope and compared with the previous data Result:The mean body weight six month after the operation was 116.2 ?15.2 kilo grams in comparison with 156.8 ?14.9 kilo grams at time of surgery with mean weight loss about 40.6 kilo grams and the mean body mass index six month after the operation is 40.7 ?4.4 in comparison with 55.0 ?4.7 at time of surgery with mean body mass index loss about 14. Normal gastric mucosa increased to 12 cases (48%) six month post-operative in comparison to seven cases (28%) at time of operation and Pathologic gastric mucosa decreased to 13 cases (52%) six month post-operative in comparison to 18 cases (72%) at time of operation Conclusion: Open duodenal switch operation (Single Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy) for morbidly obese patients gives very good results in weight loss and control of diabetes mellitus type II and hypertension. As regards the epithelial changes after surgery it was noticed that there were improvement of the gastric mucosal pathology.

Article Analytics

References

  1. Adair JD and Pleatman MA. Definition of Obesity and Indications for Surgery. In "The SAGES Manual: A Practical Guide to Bariatric Surgery", Nguyen NT, DeMaria EJ, & Ikramuddin S, (Eds.); New York: Springer Science+Business Media, LLC, 2008 4: 27-30.
  2. World Health Organization (2016). Obesity and overweight .[cited 2016 August 15]. Available from http://www.who/int/mediacentre/factsheets/fs311/en.
  3. El Ansari W, El Ashker S and Moseley L. Associations between Physical Activity and Health Parameters in Adolescent Pupils in Egypt.Int J Environ Res Public Health 2010; 7: 1649-1669.
  4. Li Z,Bowerman S, Heber D (2005) Health ramifications of the obesity epidemic. Surg Clin North Am 85: 681-70, v.
  5. Kitahara CM, Flint AJ, BerringtondeGonzalez A, et al Association between class III obesity (BMI of 40-59 kg/m2) and mortality: a pooled analysis of 20 prospective studies. PLoSMed 2014 Jul8; 11(7): e1001673.doi:10.1371/journal.pmed.1001673
  6. SchirmerB, SchauerPR. The surgical management of obesity. In: Brunicardi , AndersenD, HunterJ, et al., editors. Schwartz?s principles of surgery ninth edition. USA: McGraw-HillCompanies p.952?3 2010
  7. vanRutte PW, Smulders JF, deZoete JP, et al. Outcome of sleeve gastrectomy as a primary bariatric procedure.BrJSurg https://doi.org/10.1002/bjs.9447.8-661:(6)101 2014
  8. Ko renkov M (2006) Bariatric surgery. Contrib Nephrol 151: 243-253
  9. Ren CJ, Patterson E, Gagner M. Early results of laparoscopic biliopancreatic diversion with duodenal switch: a case series of 40 consecutive patients. Obes Surg 2000;10:514-23; discussion 524.
  10. HimpensJ, DobbeleirJ, PeetersG. Long-term results of laparoscopic sleeve gastrectomy for obesity. AnnSurg.2010;252(2):319?24.
  11. S?nchez-Pernaute A, Rubio Herrera MA, P?rez-Aguirre E, et al. Proximal duodenal-ileal end to- side bypass with sleeve gastrecto- my: proposed technique. Obes Surg. 2007;17:1614?8.
  12. Abd-Elatif A, Youssef T, Farid M, Ali Y, Gado W (2015) Nutritional Markers after Loop Duodenal Switch (SADI-S) for Morbid Obesity: A Technique with Favorable Nutritional Outcome. J Obes Weight Loss Ther 5: 268. doi:10.4172/2165-7904.1000268
  13. Canil, A.M., Iossa, A., Termine, P. et al. OBES SURG (2018) 28: 1760. https://doi.org/10.1007/s11695-017-3092-9
  14. Safaan, T., Bashah, M., El Ansari, W. et al. OBES SURG (2017) 27: 1741. https://doi.org/10.1007/s11695-016-2525-1
  15. Nelson L etal. Safety and effectiveness of single anastomosis duodenal switch procedure: preliminary results from a single institution. ArqBrasCirDig.2016;29(Suppl1):80?4.
  16. van den Heuvel M, H?rchner R, Wijtsma A, Bourhim N, Willemsen D, et al. (2011)? Sweet? eating:? a? definition? and? the? development? of? the Dutch Sweet Eating Questionnaire. Obes Surg 21: 714-721.
  17. Onzi TR, Acampora A, Ara?jo FM, Baratieri R, Kremer G, LyraJr HF and Leit?o JT.Gastric Histopathology in Laparoscopic Sleeve Gastrectomy: Pre- and Post-Operative Comparison OBES SURG (2014)24:371?376 DOI 10.1007/s11695-013-1107-8

How to Cite This Article

Atef mohamed abdel latif, mokhtar fareed abuelhoda, yaser ali elsayed, tamer youssef mohammed, ehab atef abdel- latif and amr esam el-okda. (2018); GASTRIC MUCOSAL CHANGES IN DUODENAL SWITCH OPERATION IN MANAGEMENT OF MORBID OBESITY:PRE- AND POST-OPERATIVE COMPARISON., Int. J. of Adv. Res., 6 (11), 790-797, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/8060

Corresponding Author

Amr Esam El-Okda
General surgery specialist- ministry of health- Egypt
Creative Commons Attribution 4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.