24Jan 2019

CASE REPORT OF MASSIVE RECURRENT PERICARDIAL EFFUSION SECONDARY TO HYPOTHYROIDISM.

  • Cardiology B service, Ibn Sina hospital-Rabat. Morocco.
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Background:Although relatively rare, pericardial effusions secondary to hypothyroidism have been well described (1). Moderate to large pericardial effusions are rare and associated tamponade is extremely rare (2). A wide variety of conditions can cause a pericardial effusion. Early recognition of a pericardial effusion and its underlying cause are important for improving prognosis and can avoid unnecessarily invasive investigations. Case presentation:62-year-old female patient without cardiovascular risk factors and treated for depression, admitted for the management of a state III dyspnea with severe asthenia Malaise and general weakness were also noted. The Cardiovascular Examination finds: Decreased Heart Sounds, with Signs of Right Heart Failure including Jugular Vein Turgescence with Hepatic jugular Reflux and Hepatomegaly, as well as lower limb edema reaching mid-leg. Pleuropulmonary examination found: VM decreased at baseline SpO2 = 80%. Abdominal examination found: Hepatomegaly. EKG:Sinuses and regular Rhythm at 80 BPM. And a diffuse Micro Voltage Chest X-ray:shows cardiomegaly with a CTI> 0.6 and bilateral hilar overload with bilateral basithoracic pleural effusion. Transthoracic echocardiography was performed urgently at admission, which revealed circumferential pericardial effusion of great abundance. The patient benefited the same day from a pericardial puncture with good clinical evolution. The transthoracique echocardiography shows the persistence of low to moderate abundance of pericardial effusion, without pathological respiratory variations. No collapse of the VD-OD The thoracoabdominopelvic CT scan shows the pericardial effusion and a sequential coronal renal notch.Biologically assessment: the patient has normochromic normocytic anemia with leucopenia (neutropenia) and hypothyroidism. The patient is transferred to cardiovascular chirurgical department for drainage and pleuropericardial window under medical treatment Conclusion:Hypothyroidism should be ruled out in all patients with an unexplained pericardial effusion. The corollary is that, in hypothyroid patients, other more common causes of a pericardial effusion should be excluded. In patients with a large pericardial effusion due to hypothyroidism, cardiac tamponade may be present without significant tachycardia.


  1. Hardisty CA, Naik DR, Munro DS. Pericardial effusion in hypothyroidism. ClinEndocrinol 1980;13:359?64.
  2. Manolis AS, Varriale P, Ostrowski RM. Hypothyroid cardiac tamponade. Arch Intern Med 1987;147:1167?9.
  3. Gupta R, Munyak J, Haydock T, Gernsheimer J. Hypothyroidism presenting as acute cardiac tamponade with viral pericarditis. Am J Emerg Med 1999;17:176?8.
  4. Zimmerman J, Yahalom J, Bar-On H. Clinical spectrum of pericardial effusion as the presenting feature of hypothyroidism. Am Heart J 1983;106:770 ?1.
  5. Lin CT, Liu CJ, Lin TK, Chen CW, Chen BC, Lin CL. Myxedema associated with cardiac tamponase. Jpn Heart J 2003;44:447?50.
  6. Kabadi UM, Kumar SP. Pericardial effusion in primary hypothyroidism. Am Heart J 1990;120:1393?5.
  7. Wilkes JD, Fidias P, Vaickus L, Perez RP. Malignancy-related pericardial effusion. 127 cases from the Roswell Park Cancer Institute. Cancer 1995;78:1377? 87.
  8. Kawa MP, Grymuła K, Paczkowska E, Baśkiewicz-Masiuk M, Dąbkowska E, Koziołek M, et al. Clinical relevance of thyroid dysfunction in human haematopoiesis: biochemical and molecular studies.?Eur J Endocrinol.?2010;162(2):295?305.?[PubMed]
  9. Reed HL. Circannual changes in thyroid hormone physiology: the role of cold environmental temperatures. Arctic Med Res 1995; 54(Suppl 2):9 ?15.
  10. Lindsay RS, Toft AD. Hypothyroidism. Lancet 1997;349:413?7.
  11. Helfand M, Redfern CC. Clinical guideline, Part 2. Screening for thyroid disease: an update. Ann Intern Med 1998;129:144 ?58.
  12. Mandavia DP, Hoffner RJ, Mahaney K, Henderson SO. Bedside echocardiography by emergency physicians. Ann Emerg Med 2001;38:377? 82.
  13. Sagrista-Sauleda J, Merce J, Permanyer-Miralda G, Soler-Soler J. Clinical clues to the causes of large pericardial effusion. Am J Med 2000;109:95?101.
  14. Soler-Soler J, Sagrista-Sauleda J, Permanyer-Miralda G. Management of pericardial effusion. Heart 2001;86:235? 40.
  15. Khaleeli AA, Memon N. Factors affecting resolution of pericardial
  16. effusions in primary hypothyroidism: a clinical, biochemical and echocardiographic study. Postgrad Med J 1982;58:473? 6.

[Y.Kettani, N.Azib, S. Hallab, L.Oukerraj and M. Cherti. (2019); CASE REPORT OF MASSIVE RECURRENT PERICARDIAL EFFUSION SECONDARY TO HYPOTHYROIDISM. Int. J. of Adv. Res. 7 (Jan). 1294-1299] (ISSN 2320-5407). www.journalijar.com


YOUNESS KETTANI
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Article DOI: 10.21474/IJAR01/8452      
DOI URL: https://dx.doi.org/10.21474/IJAR01/8452