EVALUATION OF INTERFERON- γ LEVEL IN ASTHMA PATIENTS.
- MB ChB, MSc. (Immunological disease), A specialist physician, Al-Yarmouk Teaching Hospital.
- MB ChB, DG&O, Gynecologist, Al-Yarmouk Teaching Hospital.
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Abstract
Background: Bronchial asthma is a chronic inflammatory disease of the airways. It manifests with recurrent episodes of coughing, breathlessness, wheezing, and chest tightness. There is a noticeable increase in health care burden from asthma in several areas of the world. In asthmatic patients the reduced production of IFN-γ has been reported.
Methodology: A total of 53 individuals were included in a comparative study. Full history was taken especially regarding the family history, disease presentation, in addition to careful physical examination. Serum IFN- γ assessment, WBC count, and Eosinophil count were measured.
Results: The study covered 37 patients with bronchial asthma, and 16 apparently healthy individual as a control group. The highest rate 27% was in the age group of (20-29) year. There was no statistical significant difference between severity of asthma and residence of the patients (p=0.893). IFN- γ was significantly higher in those with bronchial asthma in comparison with control group (p=0.00001).
Conclusion: All asthmatics have low serum IFN-γ level but high eosinophil count. Further detailed study of IFN-γ effectiveness in asthmatic patients, also carrying out a clinical trial about the use of IFN-γ in the treatment of asthma.Considering its role in treatment.
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How to Cite This Article
Ahmed Saeed Abdul-Jabbar and Emad T. Ahmed. (2019); EVALUATION OF INTERFERON- γ LEVEL IN ASTHMA PATIENTS., Int. J. of Adv. Res., 7 (04), 23-28, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/8785
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