AN EXPERIMENTAL EVALUATION OF ARTAVAJANAKA YOGA ON FEMALE REPRODUCTIVE SYSTEM W. S. R TO AMENORRHOEA.

Femininity is related with menstruation and reproduction. Menstruation may be defined as periodic and cyclical shedding of the progestational endometrium accompanied by loss of blood and so, sometimes described as ?the weeping of a disappointed uterus?. It takes place at approximately 28 day intervals between menarche and menopause. If any of the components of the HPO axis are non-functional, pathologies arise leading to conditions like amenorrhoea where bleeding may not occur. A cyclic change in the endometrium includes regeneration and proliferation of the endometrium is done by estrogen. Withdrawal of estrogen causes shedding of the endometrium and menstruation. AcharyaSushruta says that aggravated vata and kapha obstructs the passage of artava thus artavapravrutti does not takes place; clinical features of secondary amenorrhoea can be seen or understood in nashtartava1. Amenorrhea literally means absence of menstruation which is a symptom and not a disease. Evaluation and management of a patient with amenorrhea is common in gynecology and the prevalence of pathological amenorrhea ranges from 3 to 4 percent in reproductive aged population. Common causes of secondary amenorrhea are Stress, Post pills, Psychotropic and Antihypertensive drugs, Pituitary Adenoma and Sheehan?s Syndrome, PCOS, Premature ovarian failure, Uterine synechiae, Malnutrition, hypothyroid state and Diabetes.2 The treatment opted in modern system of medicine is hormonal therapy, which may have adverse effects on body like obesity, nausea, vomiting, endometrial cancer, breast cancer and liver diseases. So, to prevent all these hazards and to maintain healthy life, safe Ayurvedic non-hormonal drug formulation as quoted in BhaishajyaRatnavaliYonivyapadrogadhikar is proposed. In Ayurveda classics Jyotishmati plant is a artavapravartaka3 and the qualities of this plant are katu-tikta rasa, tiksna, snigdha, saraguna, usnavirya, katuvipaka, medhya, and vatakaphasamaka4. Since it is the need for safe, effective and yet economical drugs which is free of side effects and easily available. So, an aim to do a preclinical study to know the effect of artavajanaka yogaon anartava is evaluated.