22Jun 2019

ADULT HEPATIC MESENCHYMAL HAMARTOMA: A CASE REPORT.

  • Department of general surgery, Avicenna Military Hospital, Marrakesh.
  • Department of pathology, Avicenna Military Hospital, Marrakesh.
Crossref Cited-by Linking logo

  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

The mesenchymal hamartoma of the liver is a benign hamartomatous lesion whose pathogenesis is unknown. It usually occurs in children and has been rarely reported in adults. We report an unusual case of a cystic mesenchymal hamartoma of liver in an 65-year-old elderly female. A provisional diagnosis of gastrointestinal stromal tumor (GIST) was made and definitive histopathology confirmed the diagnosis. This case has been reported because of its rarity.

  1. Yen JB, Kong MS, Lin JN. Hepatic mesenchymal hamartoma. J Paediatr Child Health 2003; 39:632‑
  2. Wada M, Ohashi E, Jin H, Nishikawa M, Shintani S, Yamashita M, et al. Mesenchymal hamartoma of the liver: Report of an adult case and reviewof the literature. Intern Med 1992; 31:1370‑
  3. Edmondson HA: Differential diagnosis of tumors and tumor-like lesions of liver in infancy and childhood. Am J Dis Child 1956; 91:168?186.
  4. Karpelowsky JS, Pansini A, Lazarus C, Rode H, Millar AJ. Difficulties in the management of mesenchymal hamartomas. Pediatr Surg Int 2008;24:1171‑
  5. Cook JR, Pfeifer JD, Dehner LP. Mesenchymal hamartoma of the liver in the adult: Association with distinct clinical features and histological changes. Hum Pathol 2002;33:893‑
  6. Laberge JM, Patenaude Y, Desilets V, Cartier L, Khalife S, Jutras L, Chen MF: Large hepatic mesenchymal hamartoma leading to midtrimester fetal demise. Fetal Diagn Ther 2005; 20:141?145.
  7. Sharma M, Bansal P, Goyal NK. Adult hepatic mesenchymal hamartoma: An unusual case. J Lab Physicians 2014; 6:124-6.
  8. Chau KY, Ho JW, Wu PC, Yuen WK: Mesenchymal hamartoma of liver in a man: Comparison with cases in infants. J Clin Pathol 1994;47:864?866.
  9. Yesim G, Gupse T, Zafer U, Ahmet A: Mesenchymal hamartoma of the liver in adulthood: immunohistochemical profiles, clinical and histopathological features in two patients. J Hepatobiliary Pancreat Surg 2005;12:502?507.
  10. Mortele KJ, Ros PR: Cystic focal liver lesions in the adult: differential CT and MRI imaging features. Radiographics 2001;21:895?910.
  11. Talmon GA, Cohen SM. Mesenchymal hamartoma of the liver with an interstitial deletion involving chromosome band 19q13.4: A theory as to pathogenesis? Arch Pathol Lab Med 2006;130:1216‑
  12. Lauwers GY, Grant LD, Donnelly WH, Meloni AM, Foss RM, Sanberg AA, Langham MR Jr: Hepatic undifferentiated (embryonal) sarcoma arising in a mesenchymal hamartoma. Am J Surg Pathol 1997;21:1248?1254.
  13. 13 .Begueret H, Trouette H, Vielh P, Laurent C, MacGrogan G, Delsol M, Belleannee G, Masson B, De Mascarel A: Hepatic undifferentiated embryonal sarcoma: malignant evolution of mesenchymal hamartoma? Study of one case with immunohistochemical and flow cytometric emphasis. J Hepatol 2001;34:178?179.
  14. Li O, Wang J, Sun Y, Cui Y, Hao X: Hepatic angiosarcoma arising in an adult mesenchymal hamartoma. Int Semin Surg Oncol 2007;4:3.
  15. Zachary Klaassena, Prakash R. Paragi, Ronald S. Chamberlain . Adult Mesenchymal Hamartoma of the Liver: Case Report and Literature Review . Case Rep Gastroenterol 2010;4:84?92 .

[Ahmed Elguazzar, Ahmed Zeroual, Amine Azami, Mohamed Lahkim, Ahmed Elkhader and Rachid Elbarni. (2019); ADULT HEPATIC MESENCHYMAL HAMARTOMA: A CASE REPORT. Int. J. of Adv. Res. 7 (Jun). 1008-1011] (ISSN 2320-5407). www.journalijar.com

Ahmed Elguazzar
Department of general surgery, Avicenna military hospital, Marrakesh

DOI:

Article DOI: 10.21474/IJAR01/9305      
DOI URL: https://dx.doi.org/10.21474/IJAR01/9305

Download Full Paper

Download PDF No. of Downloads: 22 | No. of Views: 76