Vol. 8 (03) pp. 728-730 DOI: 10.21474/IJAR01/10685

A CASE REPORT ON AMOXICILLIN INDUCED TOXIC EPIDERMAL NECROLYSIS

  • Department of General Medicine, Aster CMI Hospital, No. 43/2, New Airport Road, NH 44, Sahakar Nagar, Hebbal, Bengaluru, Karnataka 560092.
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Abstract

Adverse drug reactions are unintended hazardous effects of drug that can occur with any class of medication;however studies have shown a high incidence with antibiotics. Amoxicillin is a broad spectrum beta lactam antibiotic, commonly used in treating infections, is known to cause cutaneous skin eruptions. Toxic epidermal necrolysis (TEN) is a rare but severe life threatening dermatological reaction most often triggered by medications. Here we describe a case of TEN in a 69 year old male following Amoxicillin therapy presenting with mucocutaneous lesions with super added multidrug resistant bacterial infection requiring 20 days of rigorous hospital care.

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References

  1. Obeid G, Valecyric-Allanore L, Wolkestein, P. European Handbook of Dermatological Treatments: 2015;971-82.
  2. Harris V, Jackson C, Cooper A. Review of Toxic Epidermal Necrolysis. Int. J. Mol. Sci: 2016;(17):1-10.
  3. Roujeau JC, Kelly JP, Naldi L, Rzany B, Stern RS, Anderson T et al. Medication use and the risk of Stevens?Johnson syndrome or toxic epidermal necrolysis.?N Engl J Med.?1995;333:1600?7.
  4. Harr T, French LE, Toxic epidermal necrolysis andStevens -Johnson syndrome. Biomed 2010;(5):1-11.
  5. Erdogen S, Uzger A, San M, Toxic Epidermal Necrolysis: A case report. J Clin Anal Med 2016;7(5):740-2.
  6. Klancir T, Adam V N, Matolic, M et al, Antibiotic induced Toxic Epidermal necrolysis- A Case Report. ActaDeramatpvenerol Croat 2017;25(1):72-6.
  7. RasoolQadir SN, Raza N, Qudir F. Drug induced toxic epidermal necrolysis: two case reports. Cases J. 2009;2:7765.
  8. Patel JB, Agarwal P, Soitawala S, Sattigeri B N. Amoxicillin induced toxic epidermal necrolysis(TEN) : a case report. Int J Res Med Sci. 2015;3(4):1011-4.
  9. Schopf E, Stuhmer A, Ranzy B, Victor N, Zentgraf R, KappJF. Toxic Epidermal Necrolysis and Stevens Johnson Syndrome. An epidemiologic study from West Germany. Arch Dermatol 1991; 127(6):839-42.
  10. Zachariah TG, Sathyanarayana KN, Noronha TM et al. Amoxicillin induced toxic epidermal necrolysis; a case report. IJBCP 2016;5(3):1134-7.

How to Cite This Article

K.V.S. Reddy, S.N. Padmini, Chaithanya D. Shetty, Alan Kuriakose and Jasna V (2020); A CASE REPORT ON AMOXICILLIN INDUCED TOXIC EPIDERMAL NECROLYSIS, Int. J. of Adv. Res., 8 (03), 728-730, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/10685

Corresponding Author

Dr K V S Reddy
Internal Medicine