STUDY ON CLINICAL CORRELATION BETWEEN MIGRAINE AND MOOD DISORDERS
- MD Psychiatry, Professor Department of Psychiatry, Career Institute of Medical Sciences and Hospital, Lucknow.
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Background: It has been definitely established by numerous populations and clinical research studies that mood disorders are comorbid with migraine with a frequency more than would be expected by chance. Aim and Objectives: The present study was done to establish that mood disorders are comorbid with migraine with increased disability and to identify any clinical features in migraineurs which may be associated with mood disorders. Material and Methods: It was a hospital based cross sectional study. The index cases were obtained from patients attending the Psychiatry Outpatient of a tertiary care hospital (Career Institute of Medical Sciences) during a period from March 01, 2018 to February 28, 2019. The cases were identified to have migraine by International Classification of Headache Disorder 3 beta criteria.To assess disability, Migraine Disability Assessment Questionnaire (MIDAS) was applied to all patients.The presence of concurrent anxiety and mood disorders was assessed by the Hospital Anxiety and Depression Scale (HADS). Results: A total of 200 patients were studied during the study. The sample consisted mostly (n = 168, 84%) of middle age (25?50 years) individuals with mean (standard deviation [SD]) of age of 35.13 (8.59) years. It was a female predominant sample (n = 140, 70%). As per HADS score, among the 22 patients (11%) suffering from depressive symptoms, 45.5% (n = 10) had borderline abnormal score and 54.5% (n = 12) had abnormal score whereas among the 32 persons (16%) suffering from anxiety 21.9% (n = 7) had borderline score and 78.1% (n = 25) had abnormal score. Conclusion: We found a prevalence of 16% of anxiety and 11% of depression in migraineurs, a rate comparable to or less than many studies in international literature and a significantly increased disability in individuals with comorbid mood disorders and migraine. Routinely including questionnaires such as HAD in screening patients with migraine to rule out comorbid mood disorders may be warranted.
- Feinstein AR. The pre-therapeutic classification of co-morbidity in chronic disease.?J Chronic Dis.?1970;23:455?68.
- Baskin SM, Lipchik GL, Smitherman TA. Mood and anxiety disorders in chronic headache.?Headache.?2006;46(Suppl 3):S76?87.
- Antonaci F, Nappi G, Galli F, Manzoni GC, Calabresi P, Costa A, et al. Migraine and psychiatric comorbidity: A review of clinical findings.?J Headache Pain.?2011;12:115?25.
- Breslau N. Psychiatric comorbidity in migraine.?Cephalalgia.?1998;18(Suppl 22):56?8.
- May A, Schulte LH. Chronic migraine: Risk factors, mechanisms and treatment.?Nat Rev Neurol.?2016;12:455?64.
- Smitherman TA, Maizels M, Penzien DB. Headache chronification: Screening and behavioral management of comorbid depressive and anxiety disorders.?Headache.?2008;48:45?50.
- Stewart WF, Lipton RB, Dowson AJ, Sawyer J. Development and testing of the migraine disability assessment (MIDAS) questionnaire to assess headache-related disability.?Neurology.?2001;56:S20?8.
- Zigmond AS, Snaith RP. The hospital anxiety and depression scale.?Acta Psychiatr Scand.?1983;67:361?70.
- Lipton RB, Hamelsky SW, Kolodner KB, Steiner TJ, Stewart WF. Migraine, quality of life, and depression: A population-based case-control study.?Neurology.?2000;55:629?35.
- Zwart JA, Dyb G, Hagen K, ?deg?rd KJ, Dahl AA, Bovim G, et al. Depression and anxiety disorders associated with headache frequency. The?Nord-Tr?ndelag health study.?Eur J Neurol.?2003;10:147?52.
- Wacogne C, Lacoste JP, Guillibert E, Hugues FC, Le Jeunne C. Stress, anxiety, depression and migraine.?Cephalalgia.?2003;23:451?5.
- Breslau N, Davis GC. Migraine, physical health and psychiatric disorder: A prospective epidemiologic study in young adults.?J Psychiatr Res.?1993;27:211?21.
- Oedegaard KJ, Neckelmann D, Mykletun A, Dahl AA, Zwart JA, Hagen K, et al. Migraine with and without aura: Association with depression and anxiety?disorder in a population-based study. The HUNT study.?Cephalalgia.?2006;26:1?6.
- Devlen J. Anxiety and depression in migraine.?J R Soc Med.?1994;87:338?41.
- Merikangas KR, Angst J, Isler H. Migraine and psychopathology. Results of the Zurich cohort study of young adults.?Arch Gen Psychiatry.?1990;47:849?53.
- Baldacci F, Lucchesi C, Cafalli M, Poletti M, Ulivi M, Vedovello M, et al. Migraine features in migraineurs with and without anxiety-depression symptoms: A hospital-based study.?Clin NeurolNeurosurg.?2015;132:74?8.
- Smitherman TA, Kolivas ED, Bailey JR. Panic disorder and migraine: Comorbidity, mechanisms, and clinical implications.?Headache.?2013;53:23?45.
- Saunders K, Merikangas K, Low NC, Von Korff M, Kessler RC. Impact of comorbidity on headache-related disability.?Neurology.?2008;70:538?47.
- De Benedittis G, Lorenzetti A. The role of stressful life events in the persistence of primary headache: Major events vs.daily hassles.?Pain.?1992;51:35?42.
- Stronks DL, Tulen JH, Pepplinkhuizen L, Verheij R, Mantel GW, Spinhoven P, et al. Personality traits and psychological reactions to mental stress of female migraine patients.?Cephalalgia.?1999;19:566?74.
[Malaya Kant Singh (2020); STUDY ON CLINICAL CORRELATION BETWEEN MIGRAINE AND MOOD DISORDERS Int. J. of Adv. Res. 8 (Mar). 1051-1055] (ISSN 2320-5407). www.journalijar.com
MD Psychiatry, Professor Department of Psychiatry, Career Institute of Medical Sciences and Hospital, Lucknow.