FATAL INTRACEREBRAL HAEMORRHAGE WITH ACUTE RENAL FAILURE WITHOUT ANY LOCAL MANIFESTATION : A RARE SEQUELAE FOLLOWING SNAKE BITE

Snake bite is common entity in tropical countries . India has maximum no of snake bite related deaths . The deaths are commonly due to haemotoxic and neurotoxic properties of snake venom . Intracranial findings occur with activation of coagulation pathway by procoagulant toxins. The snake venom has some toxins and enzymes namely proteases ,prothrombinase,metalloproteinases ,collagenase ,haemorrhagins . Cerebral haemorrhage include intraparenchymal , intraventricular , subarachnoid bleed . Acute tubular necrosis is the most common renal manifestation . These patients are usually treated with polyvalent antisnake venom . They have poor prognosis once cerebral manifestations occur .