GLYCOGEN RICH CLEAR CELL CARCINOMA (GRCC): A RARE VARIANT OF BREAST CANCER

Glycogen rich clear cell carcinoma (GRCC) is a rare subtype of breast cancer. 150 cases have been reported in the literature, thus, making its prognosis unclear and vary from one literature to another. We reported a 56-year-old woman with a right breast nodule classified ACR 4. The microbiopsy made twice was negative. Benignity was therefore highly suspected. However, the tumorectomy confirmed to be a 3.2 cm glycogen-rich clear cell carcinoma without lymph node involvement. The patient was treated with chemotherapy followed by targeted-therapy (Trastuzumab /Herceptin). She is alive and free of disease for 29 months. The purpose of reporting this case is to increase the knowledge about this rare subtype of breast malignant neoplasm and chance of better survival.