CAROTID DOPPLER AS A BIOMARKER TO DETERMINE STENOSIS IN ISCHEMIC STROKE AND MANAGEMENT OF ICU PATIENT
- MBBS, M.Phil, PhD, APCA Professor & HOD –Pharmacology Jinnah medical & Dental College. Sohail University.
- M.B.B.S, MPH (USA).Registrar Jinnah medical & Dental College. Sohail University.
- MBBS, MCPS, DMRD.Senior Registrar, Radiology Department Medicare Cardiac & General Hospital.
- B.Pharm, M.Phil, PhD ( Nottingham, UK) Principal, Jinnah College of Pharmacy, Sohail University.
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Atherosclerosis is common cause of cerebrovascular diseases. Carotid Doppler is tool to determine atherosclerotic risk in patients leading to stroke. Carotid sonography isa invasive procedure and is most commonly being used. Proper management of atherosclerotic plaque and thickness could be reducing morbidity and mortality.All those patients with stroke admitted to Medicare cardiac and general hospital will be included in the study. All those patients with stroke due to intracerebral hemorrhage will be excluded from the study .Consent form was filled by the relatives of patients. Carotid Doppler was carried out external, middle and internal carotid arteries. Performa and consent form was filled by patient/ attendant. Pre and post antiplatelet and antithrombotic therapy color Doppler was done.Out of a total of 25 patients with stroke admitted or attending the walk-in clinic of medicare cardiac 7 general hospital . Intima media thickness was increased in 25 (100%) above 0.1mm ,calcified plaques were found in 20 ( 90%) patients and stenosis was less than 40% in 19 patients and above 50% in 6 patients. Control shown to have normal intima media thickness 0.1-0.6 mm , no plaques or stenosis. Carotid Doppler is found to be most useful biomarker to determine stenosis in ischemic stroke and plaque morphology also to management of intensive care unit patient.
[Samia Perwaiz Khan, Sabeeh Jaffrey, Safia Izhar and Khwaja Zafar Ahmed (2020); CAROTID DOPPLER AS A BIOMARKER TO DETERMINE STENOSIS IN ISCHEMIC STROKE AND MANAGEMENT OF ICU PATIENT Int. J. of Adv. Res. 8 (Oct). 375-380] (ISSN 2320-5407). www.journalijar.com
Sohail University
Pakistan