Vol. 9 (05) pp. 01-05 DOI: 10.21474/IJAR01/12800

CHANGES IN LIPID PROFILE AND LIPOTOXICITY IN PEOPLE WITH HYPOTALAMIC (MORBID) OBESITY

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  • Diomid Gherman Institute of Neurology and Neurosurgery, Kishinev, Moldova.
  • Associate Professors, Institute of Physiology and Sanocreatology, MECC, Kishivev, Moldova.
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Abstract

Accumulation of visceral fat causes a lipotoxic effect on the hypothalamus. Hypothalamic inflammation closes a vicious circle, aggravating the disturbance of neuroendocrine mechanisms to regulate metabolic balance, including coordination of energy consumption (during basic metabolism, physical activity, thermogenesis) and proper feeding behavior, the study group included 62 individuals (women) with obesity. Each patient met the diagnostic criteria for idiopathic hypothalamic syndrome – the neuroendocrine form with obesity.The current study shows that obesity of hypothalamic origin is associated with a dyslipidemia that progresses simultaneously with the increase of the body mass index. 

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How to Cite This Article

B. Varsan, A.Ja. Baciu and V. Fedas (2021); CHANGES IN LIPID PROFILE AND LIPOTOXICITY IN PEOPLE WITH HYPOTALAMIC (MORBID) OBESITY, Int. J. of Adv. Res., 9 (05), 01-05, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/12800

Corresponding Author

B.Varsan
Diomid Gherman Institute of Neurology and Neurosurgery, Kishinev, Moldova.
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