DETAILING DENGUE - A STUDY OF CLINICAL AND LABORATORY PROFILE OF DENGUE PATIENTS IN A TERTIARY CARE CENTRE

Background: Dengue is one of the most rapidly spreading mosquito-borne viral disease with a rapid increase in incidence in recent decades. It is a major public health concern throughout India.The objective of this study is to review the clinical manifestations and laboratory profile of dengue cases admitted in a tertiary care hospital, near Vijayawada, Andhra Pradesh.This data would help us know and compare the inter annual variation in dengue presentation in forthcoming dengue epidemics.

Methods:This is a retrospective study carried out from 1st January 2021 to 31st December 2021 in Dr.PinnamaneniSiddhardha medical college , Chinnoutpalli ,Andhra Pradesh. Patients above 18 years of age admitted with acute febrile illness and tested positive for NS1Ag or Dengue IgM were taken into study.The required data regarding their clinical presentation , haematological and biochemical profile was collected and analysed.

Results: The most common clinical presentation of dengue in our study was fever (97%)  followed by myalgia (70%), headache (69%)arthralgia (45%), rash (29%), diarrhoea (10%)retro-orbital pain (7%),nausea and vomiting (3%).34% of patients had leucopenia.25% and 5% of patients had transaminitis and elevated renal parameters respectively

Conclusions: Dengue commonly affected the male and young population. Fever, headache, myalgia ,thrombocytopenia and leukopenia were common presenting features with few patients having transaminitis and elevated renal parameters.