25Aug 2022

NECROBIOSISLIPOIDICA IN TYPE 2 DIABETES:CLINICAL CASE AND REVIEW OF THE LITERATURE

  • Department of Endocrinology, Diabetology and Metabolic Diseases. Souss Massa University Hospital, FacultyofMedicineandPharmacy,Ibn ZohrUniversity,Agadir,Morocco.
  • Dept.ofEndocrinology,DiabetologyandMetabolicDiseasesAvicenneMilitaryHospital,Marrakech,Morocco.
  • FacultyofMedicineandPharmacy,Cadi-AyyadUniversity, Marrakech,Morocco.
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Necrobiosis lipoidica is a rare chronic granulomatous disease, often associated with diabetes mellitus. It is due to collagen degeneration with risk of ulceration. Necrobiosis lipoidica affects 0.3 to 1.2% of diabetic patients, mainly in the leg. Its etiology is not yet well understood. The diagnosis is usually made clinically but a skin biopsy may be necessary in case of atypical lesions. The evolution is chronic with ulceration and degeneration into squamous cell carcinoma as the main complications, which remains exceptional. Several therapies have been proposed: topical corticosteroids in the first instance, but no treatment has proven to have a lasting effective response. Diabetes control does not seem to influence the evolution of the disease. 


[Fatima Akioud, L houssaine Abainou, Sanaa El- Hadri, AyoubIdrissi, Azzelarab Meftah and Hicham Baizri (2022); NECROBIOSISLIPOIDICA IN TYPE 2 DIABETES:CLINICAL CASE AND REVIEW OF THE LITERATURE Int. J. of Adv. Res. 10 (Aug). 929-934] (ISSN 2320-5407). www.journalijar.com


AKIOUD
Department. of Endocrinology, Diabetology and Metabolic Diseases. University Hospital Center Souss Massa , Faculty of Medicine and Pharmacy, Ibn Zohr University, Agadir, Morocco
Morocco

DOI:


Article DOI: 10.21474/IJAR01/15252      
DOI URL: http://dx.doi.org/10.21474/IJAR01/15252