HISTOPATHOLOGICAL STUDY OF PAPULO-SQUAMOUS SKIN LESIONS

Introduction: The skin, largest organ in the body, has a limited number of reaction patterns to pathologicalstimuli. Therefore,clinically different lesions may show similar histological patterns. A proper histopathological study is considered the gold standard in diagnosing dermatological lesions but it has its limitations and very often a definite specific diagnosis is not possible without clinical details. In these cases , correlation of histopathological findings with clinical findings makes the diagnosis possible.

Material And Methodology: This was an observational study over a period of 2 years August 2020 to August 2022 in the Department of Pathology at tertiary care teaching hospital. A histopathological analysis of 190 papulo-squamous lesions were diagnosed microscopically after 24 hour formalin fixation, routine tissue processing and staining with H&E stain is included in the present study.

Result: Total 190 specimens were analyzed, specific histopathological diagnosis was made in all of cases.The most common papulo- squamous lesion was lichen planus which was seen in 53.6% of cases, followed by psoriasis which was seen in 25.7%cases.

Conclusion: As the papulo-squamous disorders are commonly encountered dermatological conditions,emphasize the role of clinicopathological correlation for accurate diagnosis,which aids in appropriate and effective clinical management and betterclinical outcome.