15Dec 2023

BREAST CARCINOMA WITH LOBULAR COMPONENT DISCOVERED BY THYROIDMETASTASIS: A CASE REPORT

  • Obstetrics and Gynecology Department, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, Marrakech, Morocco.
  • Abstract
  • Keywords
  • Cite This Article as
  • Corresponding Author

Objective: Breast cancer is the most common cause of cancer-related deaths and is frequently diagnosed in women worldwide. The purpose of this study is to report a case of breast carcinoma with lobular component discovered through thyroid metastasis at the Mohammed VI University Hospital in Marrakech. 

Case presentation: The patient, a 59 year old multiparous postmenopausal woman with a history of diabetes and hypertension, was referred from the ENT department for a thyroid localization of a carcinomatous process of mammary origin, incidentally discovered during total thyroidectomy + lymph node dissection. A cervical mass had been evolving for approximately 2 years.

Results: Physical examination revealed a cervical scar from thyroidectomy, along with an ulcerated lesion of the left breast measuring 2 x 2 cm in the sub-mammary groove, without palpable nodules or lymphadenopathy. Cervical CT scan showed a multinodular and heterogeneous cervical goiter, leading to the recommendation of total thyroidectomy + lymph node dissection. Histopathological examination with immunohistochemistry confirmed a thyroid localization of a mammary-origin carcinomatous process, specifically lobular type. Bilateral mammography revealed two lesions in the left upper outer quadrant and one near the left sub-mammary groove, associated with a left axillary lymph node classified as ACR 5. Biopsy of the sub-mammary lesion identified an infiltrating non-specific type of breast carcinoma with lobular differentiation, classified as luminal B. Following a multidisciplinary consultation, neoadjuvant chemotherapy AC60-Docetaxel + left patey post-chemotherapy was decided upon.

Conclusion: Breast cancer metastases to the thyroid, as observed in this study, are rare. Only a few studies (39 cases) have reported this type of breast cancer metastasizing to the thyroid, highlighting the uniqueness of this studyin a southern country.

Subject Areas: Gynecology & Obstetrics.


[Amirath A. Sanni, Habiba A. Mariam, Ahlam Bassir, Bouchra Fakhir, Karam Harou, Lahcen Boukhanni, Abderrahim Aboulfalah, Hamid Asmouki and Abderraouf Soummani (2023); BREAST CARCINOMA WITH LOBULAR COMPONENT DISCOVERED BY THYROIDMETASTASIS: A CASE REPORT Int. J. of Adv. Res. 11 (Dec). 114-119] (ISSN 2320-5407). www.journalijar.com


Amirath A. SANNI
Obstetrics and Gynecology Department, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, Marrakech, Morocco
Morocco

DOI:


Article DOI: 10.21474/IJAR01/17966      
DOI URL: https://dx.doi.org/10.21474/IJAR01/17966