SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF CHALCONES, PHENYLPYRIMIDINES DERIVATIVES BEARING DIBENZO [b,f][1,4]THIAZEPINES.

  • Research Scholar, Department of Chemistry, Saurashtra University, Rajkot, India.
  • Associate Professor, Department of Chemistry, M.G. Science Institute, Ahmedabad, India.
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Chalcones, Phenylpyrimidines derivatives showed remarkable therapeutic activity, with a view of getting to synthesis11-chlorodibenzo[b,f][1,4]thiazepine (1), 1-(4-(dibenzo[b,f][1,4]thiazepin-11-yloxy)-3-methoxyphenyl)ethan-1-one (2),(E)-1-(4-(dibenzo[b,f][1,4]thiazepin-11-yloxy)-3-methoxyphenyl)-3-(4-aryl)prop-2-en-1-ones(3a-3j) &4-substituted-6-(4-(dibenzo[b,f][1,4]thiazepin-11-yloxy)-3-methoxyphenyl)pyrimidin-2(1H)-ones (4a-4j) have been synthesized, All the synthesized compounds were characterized by TLC, IR, 1H NMR, Mass spectral data. All the synthesized compounds (3a-3j) & (4a-4j) were screened for their antimicrobial activity at 40 µg/ ml concentration.

[Viral Kariya and Manhar Parsania (2024); SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF CHALCONES, PHENYLPYRIMIDINES DERIVATIVES BEARING DIBENZO [b,f][1,4]THIAZEPINES. Int. J. of Adv. Res. (Feb). 144-152] (ISSN 2320-5407). www.journalijar.com

VIRAL HASMUKHRAI KARIYA
SAURASHTRA UNIVERSITY
India

DOI:

Article DOI: 10.21474/IJAR01/18276      
DOI URL: https://dx.doi.org/10.21474/IJAR01/18276

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