ENHANCING VIGABATRIN DELIVERY TO THE BRAIN: THE POTENTIAL OF SOLID LIPID NANOPARTICLES
- M. Pharmacy 2nd Year Student,Department of Pharmaceutics, Faculty of Pharmacy, SRIHER(DU).
- M. Pharmacy 2nd Year Student, Department of Pharmaceutics, Faculty of Pharmacy, SRIHER(DU).
- Assistant Professor, Department of Pharmaceutics, Faculty of Pharmacy, SRIHER(DU), Porur, Chennai, Tamil Nadu, India.
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Vigabatrin is a powerful and helpful drug for treating epilepsy and other neurological disorders. Unfortunately, because it cannot effectively cross the blood-brain barrier, its therapeutic use has been restricted. brain-blood barrier. This hinders the ability of drugs such as vigabatrin to reach their intended target region in the brain effectively. Solid lipid nanoparticles (SLNs) provide a potential solution to this problem. They are biocompatible and biodegradable, making it easier for drugs to penetrate the BBB. The effectiveness of solid lipid nanoparticles and their potential to improve vigabatrin transport to the brain is covered in this article. Furthermore, the purpose of using Solid lipid nanoparticles as drug delivery systems and the potential applications of this technology in the treatment of neurological conditions.
[Bharanidharan D., Thilak B. and A.C Niranjanasree (2024); ENHANCING VIGABATRIN DELIVERY TO THE BRAIN: THE POTENTIAL OF SOLID LIPID NANOPARTICLES Int. J. of Adv. Res. (Mar). 670-682] (ISSN 2320-5407). www.journalijar.com
Assistant Professor
India