30Jun 2015

The occurrence of hepatitis B and D viruses among uremic patients

  • College of Health and Medical Technology.
  • College of Health and Medical Technology.
  • Medical City, Baghdad Teaching Hospital, Laboratory Department.
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Viral hepatitis is a systemic disease primarily involves the liver, it could be caused by different type of viruses, hepatitis B virus is the cause of serum hepatitis, it is classified as a hepadna virus, it can establishes chronic infections especially in those infected early in life, HBV is a major factor in the eventual development of liver disease and hepatocellular carcinoma in these individuals. Hepatitis D virus (delta hepatitis) can be found within certain HBs Antigen particles, in blood, HDV (delta agent) contain delta antigen surrounded by HBs antigen envelope. Aim of the study: Is to determine the occurrence of Hepatitis B and D viruses in uremic patients, in relation to age and sex and to evaluate blood transfusion as a risk factor that may increase the rate of infection with these viruses. Patients materials and methods: This study was conducted during the period from August to October 2011 in Baghdad Teaching Hospital in the Medical City including 70 uremic patients, 40 patients were doing dialysis for the first time and 30 patients underwent maintenance hemodialysis dialysis compared to 20 patients representing the control group who were subjected to viral screening tests for HBV (antigen) and HDV(IgM) prior to surgery and were complaining of diseases other than renal or hepatic diseases. Results: Out of the seventy uremic patients examined for HBV Ag ,only three showed positive results two were in the age group (41-60), with only one positive case in the age group (61-80), with a mean age of 46 years, compared to one positive case in the control group at the age group (20-40). All patients and controls that were screened for HDV IgM showed negative results. 3/3 were males, no positive results were reported in the female group. Regarding blood transfusion, no positive result regarding HBV Ag were reported. Conclusions: The occurrence of HBV and HDV in uremic patients revealed no significant association regarding age and gender. Blood transfusion as a risk factor for these viruses was evaluated, yet no statistical significant difference were detected.


[Sarmad M Nsaif, Diploma, Dawood S Dawood, Aroub A.R Al-Kaisi (2015); The occurrence of hepatitis B and D viruses among uremic patients Int. J. of Adv. Res. 3 (Jun). 240-243] (ISSN 2320-5407). www.journalijar.com


Aroub A.R Al-Kaisi