31Jul 2015

Synthesis, Characterization, Antimicrobial Activity of Some Isatin-3hydrazone Schiff base

  • Department of Chemistry, Dr.Hari Singh Gour (Central) University Sagar (M.P.) 470003 India.
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In this paper, we synthesized some isatin 3hydrazone Schiff base that are Isatin -3-(methyenel)-hydrazone, Isatin -3-(ethyenel)-hydrazone, Isatin -3-(propylidene)-hydrazone by the reaction of isatin 3 hydrazone and different aldehydes. Structural analysis was done by 1HNMR, 13CNMR, and IR data. After that its antimicrobial activity was done by disk diffusion technique. All tested compounds tested against the three bacteria and two fungi and result reveal that Schiff base Isatin -3-(propylidene)-hydrazone show good anti microbial activity compare to other synthesized Schiff base.


[Arti Saxena, Ratnesh Das, Shweta Saxena (2015); Synthesis, Characterization, Antimicrobial Activity of Some Isatin-3hydrazone Schiff base Int. J. of Adv. Res. 3 (Jul). 81-85] (ISSN 2320-5407). www.journalijar.com


ARTI SAXENA