PRECLINICAL EVALUATION OF POLYHERBAL AS AN ANTI- ALZHEIMERS, BY USING IN-VITRO ANTICHOLINESTERASE ENZYME MODEL
- Graduate Student, Matoshri College of Pharmacy,Eklahare, Nashik.
- Assistant Professor, METs Institute of D.Pharmacy, Adgaon, Nashik.
- Principal, D.P. Kharde, Navjeevan College of College of Pharmacy, Nandur Shingote.
- Abstract
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Background: Alzheimers disease is a neurodegenerative brain condition that causes mild cognitive impairment and memory loss, eventually leading to dementia. With developments in medicine, there are now more people in the world trying to treat a wider range of illnesses. It has been discovered that traditional herbal treatment works well with little or no adverse effects.
Materials & Methods: There are certain chemical components in the polyherbal extract of liquorice, ginger, and hibiscus sabadariffa that have anti-Alzheimers properties.
Results & Discussion: The polyherbal extract of liquorice, ginger, and hibiscus sabadariffa has been shown to have significant inhibition up to 44.02% in the group treated with it, which supports the extracts anti-Alzheimers activity. This was determined through a dose-dependent study and statistical comparison using Graph Pad Prism, version 10.2.2 by two-way ANOVA.
[Somvanshi S.R., Talware P.R., Gaikwad Y.S., Patil R.N. and Vyavhare P.V. (2024); PRECLINICAL EVALUATION OF POLYHERBAL AS AN ANTI- ALZHEIMERS, BY USING IN-VITRO ANTICHOLINESTERASE ENZYME MODEL Int. J. of Adv. Res. (Sep). 1179-1191] (ISSN 2320-5407). www.journalijar.com
Matoshri College of Pharmacy, Eklahare, Nashik
India
