EVALUATION OF THE HDP GESTOSIS SCORE FOR PREDICTING PREECLAMPSIA IN THE FIRST TRIMESTER OF PREGNANCY

Background and Aims: Hypertensive disorders of pregnancy (HDP) particularly preeclampsia, are a leading cause of maternal and fetal morbidity and mortality worldwide.Despite advancements in screening, predicting preeclampsia remains a challenge, particularly in low-resource settings. The HDP Gestosis Score offers a simple, cost-effective tool to stratify risk by integrating established predictors. This study aimed to evaluate the utility of the HDP Gestosis Score in predicting preeclampsia during the first trimester.

Methods: This prospective study was conducted at BRD Medical College, Gorakhpur, over a one-year period, including 200 pregnant women. Participants were stratified into two groups: those with HDP scores 3 (high risk) and 3 (low risk). Data on clinical, demographic, and obstetric parameters were collected after obtaining ethical clearance and informed consent. Logistic regression and chi-square tests were used for statistical analysis. Diagnostic accuracy was evaluated using sensitivity, specificity, and area under the curve (AUC).

Results: The study demonstrated a hypertension prevalence of 47.5%, with 85 of hypertensive cases occurring in the high-risk group (HDP3).Significant predictors of hypertension included chronic hypertension (OR 18.0), gestational diabetes (OR 11.5), elevated MAP 85 (OR 2.6), and autoimmune disorders (OR 9.0). The HDP Gestosis Score exhibited high sensitivity (90%) and specificity (85%), with an AUC of 0.88, validating its predictive efficacy.

Conclusion: The HDP Gestosis Score is a reliable and cost-effective tool for early identification of preeclampsia risk, enabling timely interventions to reduce adverse outcomes. Its simplicity makes it particularly beneficial in resource-limited settings.