STUDY CHEMICAL COMPOSITION OF BORAGO OFFICINALIS L. EXTRACTION AND ANTIBACTERIAL ACTIVITY AGAINST GASTROINTESTINAL INFECTIONS

Borage (Borago officinalis L.), is an annual herbaceous plant and native to Europe, North Africa, and Asia Minor. It is an important vegetable crop which cultivated in some countries including Iraq. Also it is a medicinally important plant, many health effects have been attributed to the borage (Borago officinalis L.) plant, such as: antispasmodic, antihypertensive, antipyretic, aphrodisiac, demulcent, and diuretic properties. It is also considered useful to treat asthma, bronchitis, cramps, diarrhea, palpitations, and kidney ailments. The aim of study to evaluate antibacterial activity of extracts of Borage leaves against two species of bacterial (Escherichia coli and Staphylococcus aureus ) that were isolated in general samawah hospital labs from feces of patients with gastrointestinal infections. qualitative analysis was carried out to detect some active chemical compounds in extracts of borage, It was found that it contains phenols , flavonoids , tannins , proteins and carbohydrate . Extracts in concentration 150 mg/ml show inhibition activity in varying diameter against two bacteria (Escherichia coli and Staphylococcus aureus ) in patients with gastrointestinal infections. The study show that the aqueous extract of Borage leaves in hot temperature showed the highest inhibitory effect against the two species of bacteria (Escherichia coli and Staphylococcus aureus ) 13 mm and 22 mm a diameter, respectively.