PHYTOCHEMISTRY AND BACTERIAL SENSITIVITY OF SOME PLANTS USED AGAINST JAUNDICE AND INFECTIOUS DERMATOSES INTO KINDIA PREFECTURE (GUINEA)

This work was undertaken to contribute to the management of dermatological infections, and aims mainly to determine antibacterial potentialof plants used by traditional practitioners at the Republic of Guinea. To this end, we used the classical method to qualitatively identify the chemical groups with recognized pharmacological properties of 6 medicinal plant species used to treat dermatoses: Acanthospermumhispidum DC, Vernoniacolorata (Wild) Drake, Annona senegalensis Pers., Tamarindusindica L., Mimosa pudica L., Erythrinasenegalensis DC. The crude extracts (aqueous, hydroethanolic and methanolic) were obtained by maceration method. Antibacterial effet was carried outby determining the antibiotic potency of crude extracts using the method of liquid microdilution. Phytochemical screening showed that all six plants are rich in secondary metabolites and share common alkaloids, flavonoids, terpenes, steroids, saponosides, mucilages and reducing compounds, all of which have antimicrobial properties. The hydroethanol extract of Erythrinasenegalensis DC gave the highest yield (14.341.03%), while the lowest value was 5.830.08% corresponding to Tamarindusindica L. (aqueous extract). Antibacterial potential showed that gram-negative strains were more resistant to the extracts tested, while the most sensitive were gram-positive. The most sensitive strain to the methanolic extract of Mimosa pudica L. was Bacillus cereus ATCC 14579 with a MIC=250g/mL, and the most resistant strain to the several extracts was Salmonella typhimorium ATCC 2564 with MBC=1000 g/mL.