D-ASPARTIC ACID IN THE HUMAN BRAIN TISSUE: A LUMINOUS THEORY

Objective: Estimation of D-Aspartic Acid value in suicide victim’s brain tissue and comparing it with accidental death patient’s brain tissue samples and establishing DAA as a marker of suicide.

Methods: This is a hospital-based prospective study. Subjects of suicide cases and road traffic victims have been taken into account (N=30) in cases and controls respectively. Apart from routine mandatory informed consent, BRAIN TISSUE (Pre-frontal cortex) has been obtained from aforementioned subjects who have committed suicide and victims of road accident. And before that ethical clearance has been approved from the Institutional Human Ethics Committee-PGR, following which the study has been initiated.

Results: The output indicates that the mean for Control(Road traffic accidents) is 24.2737 and for the Case(Suicide group) is 19.5540. The mean of CONTROLS minus CASES equals 4.7197. 95% confidence interval of this difference is from 1.5361 to 7.9033. The standard deviation column shows a difference between cases and controls. Since, the p value equals as 0.0044, which is way less than 0.05, we can reject the null hypothesis which states that there is no association between the level of D-Aspartic acid and suicide and accept the alternative, which corroborates our idea that there is an association between DAA and suicide.

Conclusions: Suicide was among top 20 causes of death in 2024.The exact number of suicide death is unknown, since there are ways to commit suicide and in many areas of either India or the globe, cases go undocumented.There is no treatment available to treat suicide since it is the surcease of life, but there are ways to modify or alter one’s course of action if we get to realize, diagnose one’s impending act.With this study, we aim to achieve the role of DAA as a prognostic marker, we have the achievement among the dead, but to modify among the living, we admit, it requires more brain storming and man power.