23Jun 2025

BIOSYNTHESIS OF SILVER NANOPARTICLES FROM LEEA INDICA PLANT EXTRACT AND EVALUATE ITS ANTIMICROBIAL AND ANTICANCER ACTIVITY AGAINST PROSTATE CANCER CELL LINE

  • Department of Biotechnology, Kahers Dr. Prabhakar Kore Basic Science Research Centre, Belagavi-590010, Karnataka, India.
  • Kahers Dr. Prabhakar Kore Basic Science Research Centre, Belagavi-590010, Karnataka, India.
  • Scientist Grade 1 Dr Prabhakar Kore Basic Science Research Centre KAHER Belagavi.
  • Research Associate Dr. Prabahkar Kore Basic Science Research Centre KAHER Belagavi.
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Environmental friendly and economical production of silver nanoparticles (Ag-NPs) is achieved through green synthesis, utilizing Leea indica plant extract. These nanoparticles (NPs) are then tested for their Antimicrobial Activity measured using Minimum Bactericidal Concentration (MBC) and Minimum Inhibitory Concentration (MIC) of Ag-NPs against Staphylococcus aureus bacteria. Verification of the produced Ag-NPs is carried out using UV-vis spectroscopy Analysis using Fourier-transform infrared spectroscopy (FTIR) indicates the existence of hydroxyl and carbonyl groups in leeaindica plant extract, and hydroxyl and organic material in the Ag-NPs. The size range of the NPs is revealed by scanning electron microscopy (SEM) to be 150 300nm, with a tetra-angular shape. The purity of the Ag-NPs is confirmed through X-ray diffraction. Then the Ag-NPs were tested for the Anticancer activity against prostate cancer cell line (PC-3).

[Komal S. Patil, Shridhar Ghagane, Rubeen Nadaaf and Manjula I. Kambi (2025); BIOSYNTHESIS OF SILVER NANOPARTICLES FROM LEEA INDICA PLANT EXTRACT AND EVALUATE ITS ANTIMICROBIAL AND ANTICANCER ACTIVITY AGAINST PROSTATE CANCER CELL LINE Int. J. of Adv. Res. (Jun). 431-441] (ISSN 2320-5407). www.journalijar.com

Dr Shridhar.G.
Scientist \'Gr-II\'
India

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