GLIOBLASTOMA AND HYPOFRACTIONATED RADIOTHERAPY: A SUITABLE OPTION FOR VULNERABLE PATIENTS

Glioblastoma is the most common primary brain tumor. This disease is caracterised by poor diagnosis. The survival depends on multiples criteria as age and general conditions. The treatment is based on surgery or radiation therapy . For eldery patients or patient with low performance status PS <2, hypofractionated regimen was proposed. Two hypofractionated radiotherapy regimens were compared. The objective of the study is to analysize the efficiency of this therapeutic regimen. This study shows that hypofractionated treatment produces results in terms of global survival and progression-free survival, which are not statically significant compared with the normofractionated regimen. The hypofractionated regimen is a therapeutic alternative for patients not suitable for normofractionated treatment.