PLATELET INDICES: INDICATORS OF DIABETIC RETINOPATHY PLATELET INDICES AS NEW BIOMARKERS IN PATIENTS OF DIABETIC RETINOPATHY

Aim and Objectives: The aim of this study is to study role of platelet indices in type 2 diabetes mellitus (T2DM) with and without diabetic retinopathy. The objectives included assessing platelet count, mean platelet volume (MPV), platelet distribution width (PDW), and platelet large cell ratio(P-LCR)within these patient categories and to comparing platelet indices among healthy controls, diabetic patients without retinopathy, and those with retinopathy.

Materals and Methods : This prospective case-control study was conducted at Departments of Pathology and Ophthalmology, School of Medical Sciences & Research, Sharda Hospital, Greater Noida. Over one and a half years, 150 cases were enrolled, divided into three groups: controls, diabetic patients without retinopathy, and diabetic patients with retinopathy. The patients coming to ophthalmology opd for retina checkup, blood sample was taken. As same vial is used for both estimation of platelet indices and HBA1C, both blood investigations along with their retina findings were noted. Inclusion criteria involved adult type 2diabetes patients, with exclusions for anemia,certain eye conditions,uncontrolled hypertension,cardiovascular issues, renal failure, anti-platelet drug usage, malignancy, and type 1 diabetes were made.