EVALUATION OF THE FOLLICLE-STIMULATINGACTIVITY OF THE AQUEOUS LEAF EXTRACT OF CISSUSARALIODESON THE VAGINAL EPITHELIUM OF THE DOE (FEMALE RABBIT)

  • Laboratory of Histology, Embryology and Cytogenetics, Training and Research Unit of Medical Sciences of Abidjan, Felix Houphouet-Boigny University of Abidjan, Cote dIvoire.
  • Laboratory of Biology and Health, Training and Research Unit Biosciences, Felix Houphouet-Boigny University of Abidjan, Cote dIvoire.
  • Laboratory of Zootechnics, Training and Research Unit in Agriculture, Fisheries Resources, and Agro Industry, Polytechnic University of San Pedro, Cote dIvoire.
  • Laboratory of Histology, Embryology and Cytogenetics, Training and Research Unit of Medical Sciences of Bouake, Alassane Ouattara University of Bouake, Cote dIvoire.
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Background: Reproductive disorders representing 15-30% of the African population cause great concern for many couples of childbearing ages. Among them, more than 80% have recourse to medicinal plants for treatment. This study aims to evaluate the follicle-stimulatingactivity of the aqueous leaf extract of Cissusaraliodeson the vaginal epithelium of the doe (female rabbit).

Methods: Phytochemical screening of this extract was first performed. Then, for the follicle-stimulating activity, twelve does were divided into fourgroups of threeeach and treated daily for two weeks. Group 1, which served as the control group, received orally distilled water, while groups 2, 3, and 4 wereorally administered increasing doses of 200, 300, and 600 mg/kg body weight (b.w.) of the aqueous leaf extract of C. araliodes, respectively. Vaginal smears were taken before and during treatment to observe changes in surface cells.

[Okon Abou Joel Landry, Kouassi Konan Armand Marcelin, Coulibaly Founzegue Amadou, Goulai Bi You Etienne Bazago, Deh Zhou Patricia, Doukoure Brahima and Yao Gnangoran Victor (2025); EVALUATION OF THE FOLLICLE-STIMULATINGACTIVITY OF THE AQUEOUS LEAF EXTRACT OF CISSUSARALIODESON THE VAGINAL EPITHELIUM OF THE DOE (FEMALE RABBIT) Int. J. of Adv. Res. (Sep). 551-557] (ISSN 2320-5407). www.journalijar.com

Kouassi Konan Armand Marcelin
Laboratory of Biology and Health, Training and Research Unit Biosciences, Felix Houphouët-Boigny University of Abidjan, Côte d’Ivoire.
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