TARGET-CONTROLLED INFUSION VERSUS INTERMITTENT BOLUS ADMINISTRATION OF PROPOFOL FOR SEDATION IN COLONOSCOPY: A RANDOMIZED CONTROLLED TRIAL

  • Departement of Cardiac Anesthesia and Critical Care, Mohamed V Military Training Hospital, Rabat-Morocco.
  • Departement of Anesthesia, Mohamed V Military Training Hospital, Rabat-Morocco.
  • Heqd of Departement of Anesthesia and Critical Care, Mohamed V Military Training Hospital, Rabat-Morocco.
  • Abstract
  • Keywords
  • Cite This Article as
  • Corresponding Author

Background: Propofol is the preferred sedative agent for colonoscopy, but optimal administration techniques remain debated. This study compared target-controlled infusion (TCI) with intermittent bolus (IB) administration regarding safety, enjcacy, and patient satisfaction.

Methods:We conducted a prospective, randomized, single-center study of 100 patients (ASA I-III) undergoing elective colonoscopy. Patients were randomized to receive propofol via TCI (n=50) or IB administration (n=50). Primary endpoints included composite safety outcomes and sedation adjustments. Secondary endpoints comprised propofol consumption, recovery time, and satisfaction scores.

Conclusion: Both techniques demonstrated comparable overall safety. TCI provided superior sedation stability and patient satisfaction but required higher drug consumption and longer recovery times.Technique selection should be individualized based on patient characteristics and clinical priorities.

[A.Meskine, M.Samali, M.Bensghir, K.Aboulaala and H.Balkhi (2025); TARGET-CONTROLLED INFUSION VERSUS INTERMITTENT BOLUS ADMINISTRATION OF PROPOFOL FOR SEDATION IN COLONOSCOPY: A RANDOMIZED CONTROLLED TRIAL Int. J. of Adv. Res. (Sep). 1283-1288] (ISSN 2320-5407). www.journalijar.com

Amine Meskine
training military hospital Mohamed V -Rabat
Morocco

Download Full Paper

Download PDF No. of Downloads: 0 | No. of Views: 4