DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD FOR SIMULATANEOUS ESTIMATION OF EMPAGLIFLOZIN AND LINAGLIPTIN IN TABLET DOSAGE FORM

  • JSPMs Rajarshi Shahu College of Pharmacy and Research, Service Road, Ashok Nagar, Tathawade, Mumbai-Pune Highway, Pimpri Chinchwad, Maharashtra, 411033 India.
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This study outlines the establishment and evaluation of a straightforward, economical, as well as dependable UV-based analytical method for the assessment of Empagliflozin as well as Linagliptin both pure compounds and tablet dosage forms. Ethanol served as the solvent, with the maximum absorbance wavelengths identified at 222.80 nm for Empagliflozin and 294 nm for Linagliptin. The method underwent thorough validation as per ICH guidelinesconfirming its suitability for routine pharmaceutical analysis.A linear response was observed within ranging between 2 to 16ug/mL, showing high R-value (R2 = 0.998), which confirmed a consistent relationship between concentration and absorbance.

[Kanchan J. Ghatol, Suvarna S. Vanjari and Rajendra B. Patil (2025); DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD FOR SIMULATANEOUS ESTIMATION OF EMPAGLIFLOZIN AND LINAGLIPTIN IN TABLET DOSAGE FORM Int. J. of Adv. Res. (Oct). 1263-1275] (ISSN 2320-5407). www.journalijar.com

Kanchan Ghatol

India

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