PRURIGO NODULARIS AWARENESS, BURDEN, AND TREATMENT APPROACHES: A SYSTEMATIC REVIEW (PRISMA)
- Department of Dermatology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
- Abstract
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- Corresponding Author
Background: Prurigo nodularis (PN) is a chronic, intensely pruritic dermatosis with substantial psychosocial burden. Awareness among the public and even non dermatology clinicians remains limited, and therapeutic guidance has evolved rapidly with targeted biologics.
Objective:To systematically synthesize evidence on PN awareness and public perceptions, disease burden and quality of life, and therapeutic approaches including classical agents and emerging biologics.
Methods: Following PRISMA, we searched PubMed, Embase, and Scopus from inception to June 2025. Inclusion criteria encompassed adult PN/CNPG studies addressing awareness/perceptions, epidemiology/burden, or treatments; guidelines and consensus statements were included. Data extraction and risk of bias (RoB 2 for trials; Newcastle Ottawa for observational studies) were performed. Narrative synthesis was conducted due to heterogeneity.
[Ahmed Mohammed Baabdullah (2025); PRURIGO NODULARIS AWARENESS, BURDEN, AND TREATMENT APPROACHES: A SYSTEMATIC REVIEW (PRISMA) Int. J. of Adv. Res. (Oct). 1523-1527] (ISSN 2320-5407). www.journalijar.com
