PLACENTAL CHORANGIOMA: A RARE PLACENTAL TUMOR: A CASE SERIES OF 3 PATIENTS IN TERTIARY CARE HOSPITAL, MURSHIDABAD

The human placenta regulates the exchanges between maternal and fetal circulations, acts as a selective barrier to the fetus against xenobiotic molecules and infections. Abnormalities of the placental structure and function can cause fetal and maternal complications. Chorangioma is a rare primary vascular tumour of placenta and arises from major stem villi under the chorionic plate or at the placental margin with an incidence of about 1%. We studied restopectively for 2 years 10 months and enumerated 3 cases of placental chorangioma in our institution. Case details like mothers age, order of pregnancy, gestational age, mode of delivery, pregnancy outcome and birth weight of the children were obtained. Relevant investigations, gross features of the specimens, histopathological diagnosis of the tissues and immuhistochemical study were obtained. The patients mean age was 28 years. All cases were second gravida. Gestational age at diagnosis was mean 35 weeks. Size of the tumor ranged from 1.5 to 3 cm. Placental weight of the three cases was mean 450 g. Ultrasound scan report was available in Case 1 and 3 which were reported as placental vascular tumor. Histopathologically all cases showed capillary proliferation resembling fetal vessels in enlarged villi covered by trophoblastic epithelium. Among 3 cases 2 cases were delivered by cesarean section and one case delivered by spontaneous normal vaginal delivery. Among 3 cases, in 1 case low birth weight baby [1.8 kg] was born. While most chorangiomas are incidental findings, larger lesions [>5 cm] may be associated with adverse outcomes. Early recognition and multidisciplinary management are essential.