THYROID PROFILE CHANGES IN PREGNANCY (T3, T4, TSH)

Pregnancy brings about significant physiological and hormonal changes that impact the normal functioning of the maternal endocrine system, particularly the thyroid gland. Thyroid hormones play a vital role in maternal well-being, fetal growth, and neurological development. This comparative study analyzes the thyroid profilemTriiodothyronine (T3), Thyroxin (T4), and Thyroid-Stimulating Hormone (TSH)mamong 100 women, including 50 pregnant and 50 non-pregnant participants.The study observed that pregnant women exhibited markedly increased levels of T3 and T4, while TSH levels were significantly lower when compared to non-pregnant women. These variations arise due to human chorionic gonadotropin (HCG) stimulation of the thyroid gland and increased estrogen-mediated synthesis of thyroid-binding globulin (TBG).The findings highlight the need for trimester-specific thyroid reference ranges to prevent misdiagnosis and unnecessary treatment The research concludes that pregnancy induced thyroid changes are physiological and essential for fetal development. Regular thyroid assessment during pregnancy is crucial to prevent maternal and fetal complications.